Secretin

Generic name: Secretin
Drug class: In vivo diagnostic biologicals

Usage of Secretin

Secretin injection is used for the stimulation of pancreas secretions to help diagnose or find problems in the pancreas and to help identify the ampulla of Vater and accessory papilla during endoscopy. It is also used to help in the diagnosis of gastrinoma (tumor of the bowel or pancreas).

This medicine is to be given only by or under the supervision of a doctor.

Secretin side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Nausea

    • Less common

  • Feeling of warmth
  • redness of the face, neck, arms and occasionally, upper chest
  • stomach upset
  • vomiting

    • Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

    Before taking Secretin

    In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:

    Allergies

    Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

    Pediatric

    Appropriate studies have not been performed on the relationship of age to the effects of secretin injection in the pediatric population. Safety and efficacy have not been established.

    Geriatric

    Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of secretin injection in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults.

    Breast Feeding

    There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

    Interactions with Medicines

    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this diagnostic test, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

    Receiving this diagnostic test with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aclidinium
  • Amantadine
  • Amitriptyline
  • Amoxapine
  • Atropine
  • Belladonna
  • Benztropine
  • Biperiden
  • Brompheniramine
  • Carbinoxamine
  • Carisoprodol
  • Chlorpheniramine
  • Chlorpromazine
  • Cimetidine
  • Clemastine
  • Clidinium
  • Clomipramine
  • Clozapine
  • Cyclobenzaprine
  • Cyclopentolate
  • Cyproheptadine
  • Darifenacin
  • Desipramine
  • Dexlansoprazole
  • Dicyclomine
  • Dimenhydrinate
  • Diphenhydramine
  • Doxepin
  • EsOmeprazole
  • Famotidine
  • Fesoterodine
  • Flavoxate
  • Fluphenazine
  • Glycopyrrolate
  • Glycopyrronium Tosylate
  • Homatropine
  • Hydroxyzine
  • Hyoscyamine
  • Imipramine
  • IpratrOpium
  • Lansoprazole
  • Loxapine
  • Meclizine
  • Mepenzolate
  • Nizatidine
  • Nortriptyline
  • Olanzapine
  • Omeprazole
  • Orphenadrine
  • Oxitropium Bromide
  • Oxybutynin
  • Pantoprazole
  • Paroxetine
  • Perphenazine
  • Pimozide
  • Pipenzolate Bromide
  • Pirenzepine
  • Prochlorperazine
  • Procyclidine
  • Promethazine
  • Propantheline
  • Propiverine
  • Protriptyline
  • Rabeprazole
  • Ranitidine
  • Scopolamine
  • Solifenacin
  • Stramonium
  • Terodiline
  • Thioridazine
  • Thiothixene
  • Tizanidine
  • Tolterodine
  • Trifluoperazine
  • Trihexyphenidyl
  • Trimipramine
  • Tropicamide
  • Trospium
  • Umeclidinium

    • Interactions with Food/Tobacco/Alcohol

    Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

    Other Medical Problems

    The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:

  • Inflammatory bowel disease or
  • Vagotomy (bowel surgery)—May decrease the response to pancreas stimulation testing causing a false diagnosis.
  • Liver disease, alcoholic or other—May mask existing disease of the pancreas.

    • Relate drugs

    How to use Secretin

    A doctor will give you this medicine in a hospital. This medicine is given through a needle placed into one of your veins.

    You should not eat or drink for at least 12 to 15 hours before receiving this medicine.

    Do not take an H2 blocker at least 2 days before receiving this medicine.

    Warnings

    It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

    Do not use anticholinergic medicines together with secretin injection. This may decrease the response to pancreas stimulation testing, which may cause a false diagnosis of having a pancreas disease.

    Do not also use stomach medicines, such as a proton pump inhibitor and an H2 blocker together with secretin injection. This may cause an increase in the response to pancreas stimulation testing, which may lead to a false diagnosis of having gastrinoma (tumor in the bowel or pancreas).

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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