Segluromet
Generic name: Ertugliflozin And Metformin
Drug class:
Antidiabetic combinations
Usage of Segluromet
Segluromet contains a combination of ertugliflozin and metformin which help control blood sugar levels. Ertugliflozin works by helping the kidneys get rid of glucose from your bloodstream. Metformin works by helping your liver release lower amounts of sugar into your blood.
Segluromet is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
Segluromet is not for treating type 1 diabetes.
Segluromet side effects
Get emergency medical help if you have signs of an allergic reaction to Segluromet: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Seek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.
Call your doctor at once if you have:
Some side effects may be more likely to occur in older adults.
Common Segluromet side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Segluromet
You should not use Segluromet if you are allergic to ertugliflozin or metformin, or if you have:
If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking this medicine.
Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.
To make sure Segluromet is safe for you, tell your doctor if you have ever had:
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.
Follow your doctor's instructions about using Segluromet if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Having high blood sugar may cause complications in both the mother and the baby.
You should not use Segluromet during the second or third trimester of pregnancy.
Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.
You should not breastfeed while using this medicine.
Segluromet is not approved for use by anyone younger than 18 years old.
Relate drugs
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- Alogliptin and metformin
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- Duetact
- Empagliflozin and linagliptin
- Empagliflozin and metformin
- Empagliflozin, linagliptin, and metformin
- Ertugliflozin and metformin
- Ertugliflozin and sitagliptin
- Glimepiride and pioglitazone
- Glipizide and metformin
- Glucovance
- Glyburide and metformin
- Glyxambi
- Insulin degludec and liraglutide
- Insulin glargine and lixisenatide
- Invokamet
- Invokamet XR
- Janumet
- Janumet XR
- Jentadueto
- Jentadueto XR
- Kazano
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- Linagliptin and metformin
- Metaglip
- Metformin and pioglitazone
- Metformin and saxagliptin
- Metformin and sitagliptin
- Oseni
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- PrandiMet
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- Repaglinide and metformin
- Rosiglitazone and glimepiride
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- Saxagliptin and dapagliflozin
- Saxagliptin and metformin
- Segluromet
- Sitagliptin and metformin
- Soliqua
- Soliqua 100/33
- Steglujan
- Synjardy
- Synjardy XR
- Trijardy XR
- Xigduo XR
- Xultophy
How to use Segluromet
Usual Adult Dose of Segluromet for Diabetes Type 2:
Individualize dose based on current regimen: Initial dose: 1 tablet orally twice a day -For patients on metformin: Start with tablet containing ertugliflozin 2.5 mg and one-half total daily dose of metformin -For patients on ertugliflozin: Start with tablet containing one-half daily dose of ertugliflozin and metformin 500 mg -For patients already treated with ertugliflozin and metformin: Start with tablet that provides one-half total daily dose of ertugliflozin and one-half of similar daily dose of metformin Adjust dose based on effectiveness and tolerability Maximum daily dose: Ertugliflozin 15 mg; Metformin 2000 mg Comments: -Volume depletion should be corrected prior to therapy initiation. -Metformin dose should be gradually increased to reduce gastrointestinal side effects; taking with meals will also reduce gastrointestinal effects. -This drug is not recommended for patients with type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis. Use: As an adjunct to diet and exercise to improve glycemic control in adults with Type 2 diabetes mellitus who are not adequately controlled on a regimen containing ertugliflozin or metformin, or in patients who are already treated with both ertugliflozin and metformin.
Warnings
You should not use Segluromet if you have severe kidney disease, if you are on dialysis, or if you have diabetic ketoacidosis.
Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.
If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Segluromet.
Ertugliflozin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Get emergency medical help if you have even mild symptoms such as: unusual muscle pain, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, irregular heart rate, dizziness, or feeling very weak or tired.
What other drugs will affect Segluromet
When you start or stop taking Segluromet, your doctor may need to adjust the doses of any other diabetes medicines you use on a regular basis.
Other drugs may interact with ertugliflozin and metformin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
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The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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