Seldane

Generic name: Terfenadine
Drug class: Antihistamines

Usage of Seldane

Seldane was withdrawn from the U.S. market in 1998.

Do not take Seldane with any of the following medicines: the antifungal drugs ketoconazole (Nizoral) or itraconazole (Sporanox); the antibiotics erythromycin (E.E.S., E-Mycin, Ery-Tab), clarithromycin (Biaxin), or azithromycin (Zithromax); or the ulcer drug cimetidine (Tagamet, Tagamet HB). A dangerous drug interaction could occur.

Seldane side effects

If you experience any of the following serious side effects, stop taking Seldane and call your doctor immediately or seek emergency medical attention.

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

an irregular heartbeat; or

seizures.

If you experience any of the following less serious side effects, continue taking Seldane and talk to your doctor:

drowsiness or dizziness;

headache;

nervousness;

nausea, diarrhea, or abdominal discomfort;

dry mouth; or

dry skin or itchiness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Before taking Seldane

You cannot take Seldane if you are taking any of the following medicines:

the antifungal drugs ketoconazole (Nizoral) or itraconazole (Sporanox);

the antibiotics erythromycin (E.E.S., E-Mycin, Ery-Tab), clarithromycin (Biaxin), or azithromycin (Zithromax); or

the ulcer drug cimetidine (Tagamet, Tagamet HB).

A dangerous side effect involving irregular heartbeats could occur if you take Seldane with any of the medicines listed above.

Before taking this medication, tell your doctor if you have

asthma or another lung disease;

low potassium levels in your blood;

urinary retention or an enlarged prostate;

kidney or liver disease; or

heart disease, especially an irregular heartbeat.

You may not be able to take Seldane, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Seldane is in the FDA pregnancy category C. This means that it is not known whether Seldane will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. It is not known whether Seldane passes into breast milk. Do not take Seldane without first talking to your doctor if you are breast-feeding a baby.

Relate drugs

What other drugs will affect Seldane

Never take Seldane with any of the following medications:

antifungal drugs such as ketoconazole (Nizoral) and itraconazole (Sporanox);

antibiotics such as erythromycin (E.E.S., E-Mycin, Ery-Tab, others), clarithromycin (Biaxin), and azithromycin (Zithromax); or

ulcer drugs such as cimetidine (Tagamet, Tagamet HB).

A dangerous side effect involving irregular heartbeats could occur if you take Seldane with any of the medicines listed above.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

a beta-blocker (heart medication) such as propranolol (Inderal) or metoprolol (Lopressor);

a monoamine oxidase inhibitor (MAOI) antidepressant such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate);

a tricyclic antidepressant such as amitriptyline (Elavil), doxepin (Sinequan), or nortriptyline (Pamelor); or

caffeine, amphetamines, decongestants, or diet pills.

Drugs other than those listed here may also interact with Seldane. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.