Silodosin

Generic name: Silodosin
Brand names: Rapaflo
Dosage form: oral capsule (4 mg; 8 mg)
Drug class: Alpha-adrenoreceptor antagonists

Usage of Silodosin

Silodosin is an alpha-blocker that is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Silodosin may also be used for purposes not listed in this medication guide.

Silodosin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have severe dizziness, or if you feel like you might pass out.

Silodosin may cause dizziness or fainting, especially when you first start taking it. You may feel very dizzy when you first wake up or get up too fast from a sitting or lying position.

Common side effects of silodosin may include:

dizziness, feeling like you might pass out;

headache;

diarrhea;

abnormal ejaculation; or

stuffy nose, sinus pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Silodosin

You should not take silodosin if you are allergic to it, or if you have:

severe liver disease; or

severe kidney disease.

Some drugs should not be used with silodosin. Your treatment plan may change if you also use:

nefazodone;

an antibiotic--clarithromycin, telithromycin;

antifungal medicine--itraconazole, ketoconazole, posaconazole, voriconazole; or

antiviral medicine for HIV or hepatitis C--Boceprevir, cobicistat, dasabuvir, elvitegravir, indinavir, lopinavir/ritonavir, nelfinavir, ombitasvir, paritaprevir saquinavir, telaprevir, or tipranavir.

Tell your doctor if you have ever had:

low blood pressure;

kidney disease (or if you are on dialysis);

heart disease;

prostate cancer;

a condition for which you take a diuretic or "water pill"; or

if you are on a low-salt diet.

Silodosin can affect your pupils. If you need eye surgery, tell the surgeon about your use of silodosin, even if you no longer take it.

Silodosin is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown.

Not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Silodosin

Usual Adult Dose for Benign Prostatic Hyperplasia:

8 mg orally once a day with a mealComments: Patients who have difficulty swallowing may open the capsule and sprinkle the powder on a tablespoonful of applesauce. The applesauce should not be hot, and should be soft enough to be swallowed within 5 minutes without chewing and followed with 8 ounces of cool water.

Warnings

Tell your doctor about all your other medicines. Some drugs should not be used with silodosin.

What other drugs will affect Silodosin

Tell your doctor about all your current medicines. Many drugs can increase your risk of very low blood pressure while taking silodosin, especially:

medicines similar to silodosin (alfuzosin, doxazosin, prazosin, tamsulosin, or terazosin);

heart or blood pressure medication; or

sildenafil (Viagra) and other erectile dysfunction medicines.

This list is not complete and many other drugs may affect silodosin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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