Sivextro

Generic name: Tedizolid (oral/injection)
Drug class: Oxazolidinone antibiotics

Usage of Sivextro

Sivextro is an antibiotic that fights bacteria.

Sivextro is used to treat skin infections in people 12 years of age and older, including "MRSA" staph infections.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Sivextro and other antibacterial drugs, this medicine should only be used to treat infections that are proven or strongly suspected to be caused by susceptible bacteria.

Sivextro side effects

Get emergency medical help if you have signs of an allergic reaction to Sivextro: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);

numbness or tingling;

vision problems, severe headache or pain behind your eyes;

sores or white patches in your mouth or on your skin;

vaginal itching or discharge;

fast or pounding heartbeats; or

low blood cell counts - fever, chills, tiredness, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common Sivextro side effects may include:

nausea, vomiting, diarrhea;

headache;

dizziness; or

pain, swelling, bruising, redness, or a hard lump where the injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Sivextro

You should not use Sivextro if you are allergic to tedizolid.

Tell your doctor if you have recently been sick with diarrhea, a fever, cold or flu symptoms, cough, or sore throat.

Tell your doctor if you have ever had diarrhea while taking antibiotics.

Tedizolid may harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed while using tedizolid. Ask your doctor about any risk.

Sivextro is not approved for use by anyone younger than 12 years old.

Relate drugs

How to use Sivextro

Usual Adult Dose for Skin and Structure Infection:

200 mg IV or orally once a day for 6 days Use: For the treatment of acute bacterial skin and skin structure infections due to susceptible isolates of Staphylococcus aureus (including methicillin-resistant and methicillin-susceptible isolates), Streptococcus pyogenes, S agalactiae, S anginosus group (including S anginosus, S intermedius, and S constellatus), Enterococcus faecalis

Usual Pediatric Dose for Skin and Structure Infection:

12 years or older: 200 mg IV or orally once a day for 6 days Use: For the treatment of acute bacterial skin and skin structure infections due to susceptible isolates of S aureus (including methicillin-resistant and methicillin-susceptible isolates), S pyogenes, S agalactiae, S anginosus group (including S anginosus, S intermedius, and S constellatus), E faecalis.

Warnings

Sivextro should only be used to treat bacterial infections. Tedizolid does not treat viral infections (e.g., the common cold).

While it is common to feel better early in the course of therapy, Sivextro should be taken exactly as directed. Skipping doses or not completing the full course of therapy may decrease the effectiveness of the immediate treatment and increase the likelihood that bacteria will develop resistance and will not be treatable in the future.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Sivextro

Tell your doctor about all your other medicines, especially:

methotrexate;

rosuvastatin (Crestor); or

topotecan.

This list is not complete. Other drugs may interact with tedizolid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.