Skyrizi Pen

Generic name: Risankizumab
Drug class: Interleukin inhibitors

Usage of Skyrizi Pen

Skyrizi Pen is used alone or in combination in adults to treat moderate to severe plaque psoriasis and active psoriatic arthritis.

Skyrizi Pen is also used in adults to treat Crohn's disease.

Skyrizi Pen may also be used for purposes not listed in this medication guide.

Skyrizi Pen side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

You may get infections more easily, even serious or fatal infections. Call your doctor right away if you have signs of infection such as:

fever, night sweats, chills, sore throat;

mouth sores, red or swollen gums;

pale skin, easy bruising, unusual bleeding; or

chest discomfort, wheezing, dry cough or hack, rapid weight loss.

Also call your doctor at once if you have:

nausea, vomiting, skin rash; or

liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Further doses may be delayed until your infection clears up.

Common side effects of Skyrizi Pen may include:

fever, headache, tiredness;

stomach pain, joint pain, back pain;

cold symptoms such as stuffy nose, sneezing, sore throat;

pain and burning when you urinate;

fungal skin infection;

low red blood cells (anemia); or

pain, bruising, swelling, or irritation where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Skyrizi Pen

You should not use Skyrizi Pen if you are allergic to it.

Before you start using Skyrizi Pen, tell your doctor if you have any signs of infection such as fever, chills, cough, body aches, tiredness, open sores, or skin wounds, diarrhea, stomach pain, weight loss, painful urination, or coughing up blood.

Tell your doctor if you've had or been exposed to tuberculosis, or if you recently traveled. Some infections are more common in certain parts of the world, and you may have been exposed during travel.

Tell your doctor if you have or ever had:

an active or chronic infection;

tuberculosis (or if anyone in your household has tuberculosis);

recently received or are scheduled to receive any vaccine; or

liver disease.

Make sure you are current on all vaccines before you start using Skyrizi Pen.

It is not known if Skyrizi Pen will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of risankizumab on the baby.

Ask a doctor if it is safe to breastfeed while using Skyrizi Pen.

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How to use Skyrizi Pen

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

In certain cases, Skyrizi Pen is injected into a vein by a healthcare provider over 1 hour. The first 3 infusions are usually given 4 weeks apart. Treatment is continued by receiving a dose under the skin once every 8 weeks using an injector device placed on the body.

Skyrizi Pen is also injected under the skin by prefilled syringe or prefilled pen.

Ask your doctor or pharmacist if you don't understand how to use an injection.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Your healthcare provider will show you where to inject Skyrizi Pen. Do not inject into the same place two times in a row. Avoid injecting into skin that is hard, red, bruised, swollen, tender, or affected by psoriasis. Do not inject within 2 inches of your navel (belly button).

You may get infections more easily, even serious or fatal infections. You will need frequent medical tests.

Before you use Skyrizi Pen, your doctor may test you for tuberculosis or other infections.

You will need frequent blood tests to check your liver function.

Store in the original carton in a refrigerator. Protect from light and do not shake or freeze.

Take the medicine out of the refrigerator and follow the instructions to let it reach room temperature before using the medicine. Do not warm the medicine with hot water, sunlight, or a microwave.

Throw away after one use, even if there is still medicine left inside or any Skyrizi Pen that has been frozen, dropped, or damaged.

Warnings

You may get infections more easily, even serious or fatal infections. Call your doctor if you have flu symptoms, cough, night sweats, neck stiffness, confusion, or vision problems. Before you use Skyrizi Pen, your doctor should test you for tuberculosis or other infections.

What other drugs will affect Skyrizi Pen

Other drugs may affect Skyrizi Pen, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.