Solifenacin

Generic name: Solifenacin
Drug class: Urinary antispasmodics

Usage of Solifenacin

Solifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

Solifenacin oral suspension (liquid), Vesicare LS is used to treat overactive bladder caused by a neurologic disorder (such as multiple sclerosis or spinal cord injury) in children at least 2 years old when other medicines cannot be used or have not worked.

Solifenacin may also be used for purposes not listed in this medication guide.

Solifenacin side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Solifenacin may cause serious side effects. Stop using solifenacin and call your doctor at once if you have:

  • severe stomach pain, or constipation for 3 days or longer;
  • pain or burning when you urinate;
  • headache, confusion, drowsiness, hallucinations;
  • vision changes, eye pain, or seeing halos around lights;
  • little or no urination, pain or burning when you urinate;
  • dehydration symptoms--dizziness, tiredness, feeling very thirsty or hot, decreased sweating, or hot and dry skin; or
  • high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.
  • Common side effects of solifenacin may include:

  • blurred vision;
  • dry mouth, dry eyes;
  • painful urination;
  • constipation; or
  • heat stroke--decreased sweating, dry skin, dizziness, tiredness, nausea, feeling hot.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Solifenacin

    You should not use solifenacin if you are allergic to it, or if you have:

  • untreated or uncontrolled narrow-angle glaucoma;
  • a stomach disorder causing delayed emptying; or
  • if you are unable to urinate.
  • Tell your doctor if you have ever had:

  • glaucoma;
  • liver disease;
  • kidney disease;
  • trouble emptying your bladder (or you have a weak stream of urine);
  • slow digestion;
  • a blockage in your stomach or intestines; or
  • long QT syndrome.
  • It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    You should not breastfeed while using solifenacin.

    Relate drugs

    How to use Solifenacin

    Usual Adult Dose for Urinary Incontinence:

    Initial dose: 5 mg orally once dailyMaintenance dose: 5 to 10 mg orally once dailyUse: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency

    Usual Adult Dose for Urinary Frequency:

    Initial dose: 5 mg orally once dailyMaintenance dose: 5 to 10 mg orally once dailyUse: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency

    Warnings

    You should not use solifenacin if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.

    What other drugs will affect Solifenacin

    Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

    Many drugs can affect solifenacin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

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