Solriamfetol
Generic name: Solriamfetol
Brand names: Sunosi
Dosage form: oral tablet (150 mg; 75 mg)
Drug class:
Miscellaneous central nervous system agents
Usage of Solriamfetol
Solriamfetol is used to treat excessive daytime sleepiness in adults with narcolepsy or in those whose sleep is disrupted by sleep apnea.
Solriamfetol will not treat sleep apnea. Keep using your CPAP machine or other device prescribed by your doctor.
Solriamfetol may also be used for purposes not listed in this medication guide.
Solriamfetol side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Solriamfetol may cause serious side effects. Call your doctor at once if you have:
Common side effects of solriamfetol may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Solriamfetol
If you have sleep apnea, this condition should be treated for at least 1 month before you start taking solriamfetol.
Do not use solriamfetol if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Tell your doctor if you have ever had:
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of solriamfetol on the baby.
Tell your doctor if you are breastfeeding. Tell your doctor if you notice agitation, sleep problems, decreased appetite, or decreased weight gain in the nursing baby.
Solriamfetol is not approved for use by anyone younger than 18 years old.
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How to use Solriamfetol
Usual Adult Dose for Narcolepsy:
Initial dose: 75 mg orally once a day upon awakening -Dose may be doubled after 3 days based on efficacy and tolerabilityMaintenance dose: 75 to 150 mg orally once a day Maximum dose: 150 mg/day Comments:-Doses above 150 mg/day have not been shown to increase effectiveness enough to outweigh dose-related adverse reactions. -Avoid taking within 9 hours of planned bedtime because of the potential to interfere with sleep if taken too late in the day.Use: To improve wakefulness in patients with excessive daytime sleepiness associated with narcolepsy.
Usual Adult Dose for Obstructive Sleep Apnea/Hypopnea Syndrome:
Initial dose: 37.5 mg orally once a day upon awakening-Dose may be doubled at intervals of 3 days based on efficacy and tolerabilityMaintenance dose: 37.5 to 150 mg orally once a day Maximum dose: 150 mg/dayComments:-This drug does not treat the underlying airway obstruction in obstructive sleep apnea (OSA). -Prior to initiating therapy, patients should have their underlying airway obstruction treated (e.g. with continuous positive airway pressure) for at least 1 month and should continue treatment while taking this drug. -Doses above 150 mg/day have not been shown to increase effectiveness enough to outweigh dose-related adverse reactions. -Avoid taking within 9 hours of planned bedtime because of the potential to interfere with sleep if taken too late in the day.Use: To improve wakefulness in patients with excessive daytime sleepiness associated with OSA.
Warnings
Do not use solriamfetol if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
What other drugs will affect Solriamfetol
Other drugs may affect solriamfetol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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