Spesolimab

Generic name: Spesolimab
Brand names: Spevigo
Dosage form: intravenous solution (sbzo 450 mg/7.5 mL)
Drug class: Interleukin inhibitors

Usage of Spesolimab

Spesolimab is used in adults to treat a certain type of psoriasis called generalized pustular psoriasis (GPP).

Spesolimab may also be used for purposes not listed in this medication guide.

Spesolimab side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

Spesolimab may cause serious side effects. Call your doctor at once if you have:

signs of an infection--fever, chills, sweats, cough, shortness of breath, blood in your mucus, any burning when you urinate, or if you urinate more than usual.

Common side effects of spesolimab may include:

tiredness or weakness;

nausea, vomiting;

headache;

itching or itchy bumps;

bruising or blood under the skin where the injection was given; or

pain or burning when you urinate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Spesolimab

You should not use spesolimab if you are allergic to it.

Tell your doctor if you have:

tuberculosis or have been exposed to tuberculosis;

an infection that keeps returning or does not go away; or

recently received or are scheduled to receive a vaccine.

Tell your doctor if you are pregnant or breastfeeding.

Relate drugs

How to use Spesolimab

Usual Adult Dose for Pustular Psoriasis:

900 mg by intravenous infusion over 90 minutes once Comment:-One week after the initial dose, consider administering an additional 900 mg IV dose (over 90 minutes) if generalized pustular psoriasis (GPP) symptoms persist. Use: Treatment of generalized pustular psoriasis flares in adults

Warnings

Call your doctor at once if you have fever, chills, sweats, cough, shortness of breath, blood in your mucus, any burning when you urinate, or if you urinate more than usual.

What other drugs will affect Spesolimab

Other drugs may affect spesolimab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

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