Sprix Nasal Spray
Generic name: Ketorolac (nasal)
Brand names: Sprix
Drug class:
Nonsteroidal anti-inflammatory drugs
Usage of Sprix Nasal Spray
Sprix is a nonsteroidal anti inflammatory drug (NSAID). Ketorolac works by reducing substances in the body that cause pain, fever, and inflammation.
Sprix Nasal Spray is used in adult patients for the short-term (5 days or less) treatment of moderate to severe pain.
The safety and effectiveness of Sprix in patients 17 years and younger has not been established. It is not for use in children less than 2 years of age.
Sprix Nasal Spray side effects
Get emergency medical help if you have signs of an allergic reaction to Sprix (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.
Stop using Sprix and call your doctor at once if you have:
Common Sprix side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Sprix Nasal Spray
Sprix can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Ketorolac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.
You should not use Sprix nasal spray if you are allergic to ketorolac, or if you have:
Pentoxifylline or probenecid can interact with ketorolac and should not be used at the same time.
Do not use Sprix Nasal Spray if you are already taking aspirin or other NSAIDs, or using other forms of ketorolac (such as injections or pills you take by mouth).
To make sure Sprix nasal spray is safe for you, tell your doctor if you have ever had:
If you are pregnant, you should not use Sprix nasal spray unless your doctor tells you to. Using an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.
Sprix may affect ovulation, which could temporarily affect fertility (your ability to have children).
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Sprix Nasal Spray is not approved for use by anyone younger than 2 years old.
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How to use Sprix Nasal Spray
Usual Adult Dose for Pain: Nasal Spray: -Weight 50 kg or more: 31.5 mg every 6 to 8 hours (1 spray in each nostril) -Weight less than 50 kg: 15.75 mg every 6 to 8 hours (1 spray in 1 nostril) -Maximum dose; weight less than 50 kg: 63 mg -Maximum dose; weight: 50 kg or more: 126 mg.
Usual Geriatric Dose for Pain: -Nasal Spray: -Dose: 15.75 mg every 6 to 8 hours (one spray in 1 nostril) -Maximum dose: 4 doses per day (63 mg).
Warnings
You should not use Sprix if you have severe kidney disease, a bleeding or blood clotting disorder, bleeding in your brain, a stomach ulcer or history of stomach bleeding, or if you have ever had a severe allergic reaction after taking aspirin or an NSAID. Do not use Sprix Nasal Spray for longer than 5 days.
Ketorolac can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Ketorolac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.
Pentoxifylline or probenecid can interact with ketorolac and should not be used at the same time.
What other drugs will affect Sprix Nasal Spray
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Ask your doctor before using Sprix if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may interact with ketorolac, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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