Sucralfate

Generic name: Sucralfate (oral)
Brand names: Carafate
Drug class: Miscellaneous GI agents

Usage of Sucralfate

Sucralfate is used short-term (up to 8 weeks) to treat an active duodenal ulcer.

Sucralfate works mainly in the lining of the stomach and is not highly absorbed into the body. sucralfate adheres to ulcer sites and protects them from acids, enzymes, and bile salts.

Sucralfate can heal an active ulcer, but it will not prevent future ulcers from occurring.

Sucralfate may also be used for purposes not listed in this medication guide.

Sucralfate side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects of sucralfate may include:

  • constipation, diarrhea;
  • nausea, vomiting, gas, indigestion;
  • itching, rash;
  • dizziness, drowsiness;
  • sleep problems (insomnia);
  • headache; or
  • back pain.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Sucralfate

    You should not use sucralfate if you are allergic to it.

    Tell your doctor if you have ever had:

  • diabetes;
  • kidney disease (or if you are on dialysis); or
  • trouble swallowing tablets.
  • Older adults may be more sensitive to the effects of sucralfate.

    Tell your doctor if you are pregnant or breastfeeding.

    Do not give this medicine to a child without medical advice.

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    How to use Sucralfate

    Usual Adult Dose for Duodenal Ulcer:

    1 g orally 4 times a day-Duration of therapy: 4 to 8 weeksComments:-Each dose should be taken on an empty stomach.-For most patients, treatment should continue for 4 to 8 weeks; however, treatment may be stopped early if healing is demonstrated on x-ray/endoscopic tests.-Antacids may be given, but use should be separated by at least 30 minutes.Use: Short-term treatment of active duodenal ulcers

    Usual Adult Dose for Duodenal Ulcer Prophylaxis:

    Oral Tablets: 1 g orally 2 times a day-Duration of therapy: Up to 1 yearComments:-Each dose should be taken on an empty stomach.-Controlled studies did not extend beyond 12 months.Use: Maintenance therapy for patients after healing of acute duodenal ulcers

    Warnings

    The liquid form of sucralfate should never be injected through a needle into the body, or death may occur.

    What other drugs will affect Sucralfate

    Other drugs may affect sucralfate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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