Synera

Generic name: Lidocaine And Tetracaine Topical
Brand names: Synera
Drug class: Topical anesthetics

Usage of Synera

Synera patches contain a combination of lidocaine and tetracaine. Lidocaine and tetracaine are local anesthetics (numbing medicines). They work by blocking nerve signals in your body.

Synera patches are used to numb a small area of your skin. This can help prevent pain during certain medical procedures such as a skin biopsy, minor skin surgery, insertion of an intravenous (IV) needle, or other needle-stick procedures.

Synera patches are also used to numb a skin area during minor cosmetic procedures such as a Botox injection, laser treatment, or tattoo removal.

Synera side effects

Get emergency medical help if you have signs of an allergic reaction to Synera: hives; wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers or call your doctor right away if you have:

  • severe burning, stinging, or other irritation where the medicine was applied;
  • sudden dizziness or drowsiness after the medicine is applied;
  • pale, gray, or blue colored skin;
  • headache, fast heartbeats, shortness of breath;
  • tiredness, or feeling like you might pass out;
  • blurred vision, ringing in your ears; or
  • unusual sensations of hot or cold.
  • Common Synera side effects include:

  • skin redness;
  • skin swelling; or
  • changes in skin color where the medicine was applied.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Synera

    You should not use Synera if you are allergic to:

  • any type of numbing medicine; or
  • sunscreen or other skin products that contain para-aminobenzoic acid (PABA).
  • Fatal overdoses have occurred when numbing medicines were used without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). Be aware that many cosmetic procedures are performed without a medical doctor present.

    Synera skin patches are not approved for use by anyone younger than 18 years old.

    To make sure Synera is safe for you, tell your doctor if you have:

  • liver disease;
  • a blood cell disorder called methemoglobinemia (in you or a family member);
  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;
  • a condition for which you take a heart rhythm medicine; or
  • allergy to any other medicine used for anesthesia.
  • Older adults and people who are debilitated may be more sensitive to the effects of this medicine.

    Tell your doctor if you are pregnant or breastfeeding.

    If you apply lidocaine and tetracaine topical to your chest, avoid areas that may come into contact with the baby's mouth.

    The Synera transdermal patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.

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    How to use Synera

    Usual Adult Dose for Local Anesthesia:

    Apply one film topically to intact skin 20 to 30 minutes before procedure.

    Usual Pediatric Dose for Local Anesthesia:

    >= 3 yrs: Apply one film topically to intact skin 20 to 30 minutes before procedure.

    Warnings

    An overdose of numbing medicine can cause fatal side effects if too much of the medicine is absorbed through your skin. This can happen if you apply more than the recommended dose, or if you leave a Synera skin patch on too long.

    Keep both used and unused Synera skin patches out of the reach of children or pets.

    What other drugs will affect Synera

    Medicine used on the skin is not likely to be affected by other drugs you use. However, some drugs can cause conditions that may make it harmful for you to use Synera. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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