Tabrecta

Generic name: Capmatinib (tablets)
Drug class: Multikinase inhibitors

Usage of Tabrecta

Tabrecta is a prescription medicine used to treat adults with a kind of lung cancer called non-small cell lung cancer (NSCLC) that:

has spread to other parts of the body or cannot be removed by surgery (metastatic), and

whose tumors have an abnormal mesenchymal epithelial transition (MET) gene

It is not known if this medicine is safe and effective in children.

Tabrecta side effects

Tabrecta may cause serious side effects, including:

lung or breathing problems. Tabrecta may cause inflammation of the lungs that can cause death. Tell your healthcare provider right away if you develop any new or worsening symptoms, including:

cough

fever

trouble breathing or shortness of breath

Your healthcare provider may temporarily stop or permanently stop Tabrecta if you develop lung or breathing problems during treatment.

liver problems. Tabrecta may cause abnormal liver blood test results. Your healthcare provider will do blood tests to check your liver function before you start, and during treatment. Tell your healthcare provider right away if you develop any signs and symptoms of liver problems, including:

your skin or the white part of your eyes turns yellow (jaundice)

loss of appetite for several days or longer

dark or “tea-colored” urine

nausea and vomiting

light-colored stools (bowel movements)

confusion

pain, aching, or tenderness on the right side of your stomach-area (abdomen)

tiredness

weakness

swelling in your stomach-area

Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment if you develop liver problems.

risk of sensitivity to sunlight (photosensitivity). See What should I avoid while taking Tabrecta?

The most common side effects include:

swelling of your hands or feet

nausea

tiredness and weakness

vomiting

loss of appetite

changes in certain blood tests

These are not all of the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800 FDA-1088.

Before taking Tabrecta

Before taking Tabrecta, tell your healthcare provider about all of your medical conditions, including if you:

have or have HAD lung or breathing problems other than your lung cancer

have or have had liver problems

are pregnant or plan to become pregnant. Tabrecta can harm your unborn baby. Females who are able to become pregnant:

Your healthcare provider should do a pregnancy test before you start treatment.

You should use effective birth control during treatment and for 1 week after your last dose. Talk to your healthcare provider about birth control choices that might be right for you during this time.

Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment.

Males who have female partners who can become pregnant:

You should use effective birth control during treatment and for 1 week after your last dose.

are breastfeeding or plan to breastfeed. It is not known if Tabrecta passes into your breast milk. Do not breastfeed during treatment and for 1 week after your last dose.

Tell your healthcare provider about all the medicines you take or start taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

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How to use Tabrecta

Take Tabrecta exactly as your healthcare provider tells you.

Take Tabrecta tablets 2 times a day with or without food.

Swallow the tablets whole. Do not break, chew, or crush the tablets.

Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment if you have certain side effects.

Do not change your dose or stop treatment unless your healthcare provider tells you to.

If you miss or vomit a dose, do not make up the dose. Take your next dose at your regular scheduled time.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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