Tebentafusp
Generic name: Tebentafusp
Brand names: Kimmtrak
Dosage form: intravenous solution (tebn 100 mcg/0.5 mL)
Drug class:
Miscellaneous antineoplastics
Usage of Tebentafusp
Tebentafusp is used to treat adults with a type of cancer in the eye called uveal melanoma that cannot be removed by surgery or has spread.
Your doctor will make sure you have the correct tumor type to be treated with tebentafusp.
Tebentafusp may also be used for purposes not listed in this medication guide.
Tebentafusp side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.
Tebentafusp may cause serious side effects. Call your doctor at once if you have:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Common side effects of tebentafusp may include:
Before taking Tebentafusp
Tell your doctor if you have ever had:
You may need to have a negative pregnancy test before starting this treatment.
May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using tebentafusp and for at least 1 week after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using tebentafusp, and for at least 1 week after your last dose.
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How to use Tebentafusp
Usual Adult Dose for Malignant Melanoma:
20 mcg IV on Day 1, 30 mcg IV on Day 8, 68 mcg IV on Day 15, and then 68 mcg IV once a week thereafterDuration of therapy: Until unacceptable toxicity or disease progression occurComments:-Patient selection should be based on a positive human leukocyte antigen-A*02:01 (HLA-A*02:01) genotyping test.---A US FDA-approved test for the detection of HLA-A*02:01 genotyping is not currently available.Use: For the treatment of HLA-A*02:01-positive patients with unresectable or metastatic uveal melanoma
Warnings
Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.
What other drugs will affect Tebentafusp
Other drugs may affect tebentafusp, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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