Teclistamab

Generic name: Teclistamab
Brand names: Tecvayli
Dosage form: subcutaneous solution (cqyv 10 mg/mL; cqyv 90 mg/mL)
Drug class: Miscellaneous antineoplastics

Usage of Teclistamab

Teclistamab is used to treat adults with multiple myeloma who have received at least 4 treatment regimens and their cancer has returned or did not respond to a previous treatment.

Teclistamab is available only from a certified pharmacy under a special program.

Teclistamab may also be used for purposes not listed in this medication guide.

Teclistamab side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.

Teclistamab may cause serious side effects. Call your doctor at once if you have:

  • bruising, swelling, warmth, redness, oozing, or bleeding where an injection was given;
  • low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough;
  • neurological problems--headache, jerking muscle movements, rigid muscles, feeling restless, numbness and tingling, confusion, problems speaking, muscle spasms, tremors, double vision, changes in handwriting, problems walking, muscle weakness in body or face, hearing loss, burning, throbbing, or stabbing pain;
  • signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding; or
  • liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
  • Common side effects of teclistamab may include:

  • headache;
  • nausea, diarrhea;
  • tiredness, weakness;
  • joint pain, muscle pain in the back, chest, arms, and legs;
  • cold symptoms such as stuffy nose, sneezing, sore throat; or
  • fever, chills, cough with mucus, chest pain, feeling short of breath.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Teclistamab

    Tell your doctor if you have:

  • an infection.
  • You may need to have a negative pregnancy test before starting this treatment.

    May harm an unborn baby. Use effective birth control while using teclistamab and for at least 5 months after your last dose. Tell your doctor if you become pregnant.

    Do not breastfeed while using teclistamab, and for at least 5 months after your last dose.

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    How to use Teclistamab

    Follow all directions on your prescription label and read all medication guides or instruction sheets.

    Read the Patient Wallet Card about serious side effects and learn what symptoms to watch for. Keep the card with you at all times.

    Teclistamab is given by a healthcare provider as an injection under the skin in the stomach-area, thigh, or another area.

    You will need to stay in the hospital for 48 hours after some doses of teclistamab. Talk with your doctor if you have any questions.

    You may be given other medications to help prevent serious side effects. Keep taking these medicines for as long as your doctor has prescribed.

    Your treatment with teclistamab may be temporarily or completely discontinued if you have certain side effects.

    You will need medical tests before and during treatment with teclistamab.

    Warnings

    Tell your medical caregivers if you have symptoms of a serious side effect, such as fever, chills, trouble breathing, vomiting, or severe tiredness.

    Call your doctor if you have symptoms of neurological problems such as headache, jerking muscle movements, numbness and tingling, tremor, double vision, problems walking, hearing loss.

    What other drugs will affect Teclistamab

    Other drugs may affect teclistamab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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