Teflaro

Generic name: Ceftaroline
Drug class: Next generation cephalosporins

Usage of Teflaro

Teflaro is a cephalosporin (SEF a low spor in) antibiotic. It works by fighting bacteria in your body.

Teflaro is used to treat skin infections caused by bacteria in adults and newborns (at least 34 weeks gestational age and 12 days postnatal age).

Teflaro is also used to treat pneumonia caused by bacteria in adults and children 2 months of age and older.

Teflaro side effects

Get emergency medical help if you have signs of an allergic reaction to Teflaro: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);

little or no urination;

a seizure;

drowsiness, tiredness, confusion, thinking problems;

low potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, muscle weakness or limp feeling; or

low blood cell counts - sudden weakness or ill feeling, fever, chills, cold or flu symptoms, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common Teflaro side effects may include:

nausea;

diarrhea; or

rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Teflaro

To make sure Teflaro is safe for you, tell your doctor if you have:

a seizure;

an allergy to any drugs (especially penicillins);

kidney disease (or if you are on dialysis); or

intestinal problems, such as colitis.

Tell your doctor if you are pregnant or breastfeeding.

Relate drugs

How to use Teflaro

Usual Adult Dose of Teflaro for Pneumonia:

600 mg IV every 12 hours Duration of therapy: -Acute bacterial skin and skin structure infections (ABSSSI): 5 to 14 days -Community-acquired bacterial pneumonia (CABP): 5 to 7 days Uses: -For the treatment of ABSSSI due to susceptible isolates of Staphylococcus aureus (including methicillin-susceptible and -resistant isolates), Streptococcus pyogenes, S agalactiae, EscheriChia coli, Klebsiella pneumoniae, and K oxytoca -For the treatment of CABP due to susceptible isolates of S pneumoniae (including cases with concurrent bacteremia), S aureus (methicillin-susceptible isolates only), Haemophilus influenzae, K pneumoniae, K oxytoca, and E coli

Usual Adult Dose of Teflaro for Skin and Structure Infection:

600 mg IV every 12 hours Duration of therapy: -Acute bacterial skin and skin structure infections (ABSSSI): 5 to 14 days -Community-acquired bacterial pneumonia (CABP): 5 to 7 days Uses: -For the treatment of ABSSSI due to susceptible isolates of Staphylococcus aureus (including methicillin-susceptible and -resistant isolates), Streptococcus pyogenes, S agalactiae, Escherichia coli, Klebsiella pneumoniae, and K oxytoca -For the treatment of CABP due to susceptible isolates of S pneumoniae (including cases with concurrent bacteremia), S aureus (methicillin-susceptible isolates only), Haemophilus influenzae, K pneumoniae, K oxytoca, and E coli

Usual Pediatric Dose of Teflaro for Skin and Structure Infection:

Less than 2 months (gestational age at least 34 weeks and postnatal age at least 12 days): 6 mg/kg IV every 8 hours 2 months to less than 2 years: 8 mg/kg IV every 8 hours 2 years to less than 18 years (up to 33 kg): 12 mg/kg IV every 8 hours 2 years to less than 18 years (greater than 33 kg): 400 mg IV every 8 hours OR 600 mg IV every 12 hours Duration of therapy: 5 to 14 days Comments: -Drug levels in cerebrospinal fluid have not been evaluated in pediatric patients younger than 2 months. -No information available for dosing this drug in infants less than 34 weeks gestational age and younger than 12 days postnatal age. Use: For the treatment of ABSSSI due to susceptible isolates of S aureus (including methicillin-susceptible and -resistant isolates), S pyogenes, S agalactiae, E coli, K pneumoniae, and K oxytoca

Usual Pediatric Dose of Teflaro for Pneumonia:

2 months to less than 2 years: 8 mg/kg IV every 8 hours 2 years to less than 18 years (up to 33 kg): 12 mg/kg IV every 8 hours 2 years to less than 18 years (greater than 33 kg): 400 mg IV every 8 hours OR 600 mg IV every 12 hours Duration of therapy: 5 to 14 days Use: For the treatment of CABP due to susceptible isolates of S pneumoniae (including cases with concurrent bacteremia), S aureus (methicillin-susceptible isolates only), H influenzae, K pneumoniae, K oxytoca, and E coli

Warnings

You should not use Teflaro if you are allergic to Ceftaroline or to similar antibiotics, such as Ceftin, Cefzil, Keflex, Omnicef, and others. Tell your doctor if you are allergic to any drugs, especially penicillins or other antibiotics.

Use Teflaro for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Teflaro will not treat a viral infection such as the common cold or flu.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using Teflaro and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

What other drugs will affect Teflaro

Other drugs may interact with ceftaroline, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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