Tekturna HCT

Generic name: Hydrochlorothiazide And Aliskiren
Drug class: Miscellaneous antihypertensive combinations

Usage of Tekturna HCT

Tekturna HCT contains a combination of Hydrochlorothiazide and aliskiren. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Aliskiren is an anti-hypertensive (blood pressure lowering) medicine. t works by decreasing substances in the body that narrow blood vessels and raise blood pressure.

Tekturna HCT is a prescription medicine used to treat high blood pressure (hypertension).

Tekturna HCT may be used to lower high blood pressure in adults when one medicine to lower high blood pressure is not enough. It may also be used as the first choice to lower high blood pressure if your doctor determines that you are likely to need more than one medicine.

Tekturna HCT side effects

Get emergency medical help if you have signs of an allergic reaction to Tekturna HCT (hives, vomiting, severe stomach pain, dizziness, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

a light-headed feeling, like you might pass out;

little or no urination;

eye pain, vision problems;

high potassium level - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;

low potassium level - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;

low sodium level - headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; or

lupus-like symptoms - muscle or joint pain, fever, and a rash or patchy skin color that worsens in sunlight.

Common Tekturna HCT side effects may include:

dizziness, tired feeling;

high potassium;

cough;

joint pain;

diarrhea; or

flu symptoms (fever, chills, body aches).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Tekturna HCT

You should not use Tekturna HCT if you are allergic to aliskiren or hydrochlorothiazide, or if:

you are unable to urinate; or

you are allergic to sulfa drugs.

If you have diabetes, you should not use Tekturna HCT together with certain heart or blood pressure medicines, such as:

azilsartan (Edarbi, Edarbyclor), Candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, Avalide), losartan (Cozaar, Hyzaar), olmesartan (Azar, Benicar), valsartan (Diovan, Exforge, Tribenzor), Telmisartan (Micardis); or

Benazepril (Lotensin), Captopril (Capoten, Capozide), Enalapril (Vasotec, Vasoretic), fosinopril (Monopril), lisinopril (Prinivil, Zestoretic, Zestril), moexipril (Uniretic, Univasc), perindopril (Aceon), quinapril (Accupril, Accuretic), ramipril (Altace), or trandolapril (Mavik, Tarka).

You may also need to avoid taking these medicines with Tekturna HCT if you have kidney disease.

To make sure Tekturna HCT is safe for you, tell your doctor if you have ever had:

kidney disease;

liver disease;

low or high levels of potassium in your blood;

asthma or allergies;

systemic lupus erythematosus (SLE);

glaucoma;

gout;

diabetes; or

an allergy to penicillin.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Hydrochlorothiazide and aliskiren can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

Tekturna HCT is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Tekturna HCT

Usual Adult Dose for Hypertension:

Initial dose: 150 mg-12.5 mg or 150 mg-25 mg once daily Maximum dose: Aliskiren-hydrochlorothiazide 300/25 mg orally daily Comments: -The combination product may be substituted for patients receiving aliskiren and hydrochlorothiazide from separate tablets. -Tablets should be taken the same way each day, either with or without a meal. (High-fat meals decrease absorption of aliskiren substantially).

Warnings

You should not use Tekturna HCT if you are unable to urinate, or if you are allergic to sulfa drugs.

Do not use Tekturna HCT if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.

If you have diabetes, do not use Tekturna HCT together with certain heart or blood pressure medicines (such as Accupril, Benicar, Capoten, Cozaar, Diovan, Lotensin, Mavik, Prinivil, Vasotec, any many others).

Before you take Tekturna HCT, tell your doctor if you have asthma, low or high levels of potassium in your blood, kidney or liver disease, glaucoma, gout, lupus, diabetes, or an allergy to sulfa drugs or penicillin.

You should not use Tekturna HCT if you are allergic to aliskiren or hydrochlorothiazide, or if you are also using itraconazole (Sporanox) or cyclosporine (Gengraf, Neoral, Sandimmune).

Do not use potassium supplements or salt substitutes while you are taking Tekturna HCT, unless your doctor has told you to. It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

What other drugs will affect Tekturna HCT

If you take cholestyramine or colestipol, take your Tekturna HCT dose 4 hours before or 4 hours after you take the other medicine.

Tell your doctor about all your other medicines, especially:

cyclosporine;

lithium;

any heart or blood pressure medicines;

a diuretic or "water pill";

insulin or oral diabetes medicine;

a potassium supplement such as K-Dur, Klor-Con;

salt substitutes that contain potassium;

antifungal medicine - itraconazole, ketoconazole;

cholesterol medication - atorvastatin, cholestyramine, colestipol, simvastatin, Lipitor, Vytorin, Zocor; or

NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), Celecoxib, diclofenac, Indomethacin, Meloxicam, and others.

This list is not complete. Other drugs may interact with hydrochlorothiazide and aliskiren, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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