Telotristat ethyl

Generic name: Telotristat Ethyl
Brand names: Xermelo
Dosage form: oral tablet (250 mg)
Drug class: Miscellaneous GI agents

Usage of Telotristat ethyl

Telotristat ethyl is used in adults to treat carcinoid syndrome diarrhea, in combination with another medicine such as octreotide (Sandostatin).

Telotristat ethyl may also be used for purposes not listed in this medication guide.

Telotristat ethyl side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Telotristat ethyl may cause serious side effects. Stop using telotristat ethyl and call your doctor at once if you have:

  • severe constipation; or
  • severe or worsening stomach pain.
  • Common side effects of telotristat ethyl may include:

  • nausea, loss of appetite, gas;
  • headache, depressed mood;
  • swelling in your hands or feet;
  • fever; or
  • abnormal liver function tests.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Telotristat ethyl

    Tell your doctor if you have ever had liver disease.

    Tell your doctor if you are pregnant or breastfeeding.

    Not approved for use by anyone younger than 18 years old.

    Relate drugs

    How to use Telotristat ethyl

    Usual Adult Dose for Carcinoid Tumor:

    250 mg orally 3 times a dayComments:-Patients should take this drug with food.-If needed, short-acting octreotide should be given at least 30 minutes after administration of this drug.Use: Treatment of carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in patients whose diarrhea is inadequately controlled by SSA therapy

    Usual Adult Dose for Carcinoid Syndrome:

    250 mg orally 3 times a dayComments:-Patients should take this drug with food.-If needed, short-acting octreotide should be given at least 30 minutes after administration of this drug.Use: Treatment of carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in patients whose diarrhea is inadequately controlled by SSA therapy

    Warnings

    Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

    What other drugs will affect Telotristat ethyl

    Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

    Other drugs may affect telotristat ethyl, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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