Tepmetko

Generic name: Tepotinib
Dosage form: tablets, for oral use
Drug class: Multikinase inhibitors

Usage of Tepmetko

Tepmetko is a prescription medicine used to treat adults with non-small cell lung cancer (NSCLC) that:

  • has spread to other parts of the body (metastatic), and
  • whose tumors have an abnormal mesenchymal epithelial transition (MET) gene. Your healthcare provider will perform a test to make sure that Tepmetko is right for you.

    • It is not known if this medicine is safe and effective in children.

    Tepmetko side effects

    Tepmetko may cause serious side effects, including:

  • See Important information
  • Liver problems. Tepmetko may cause abnormal liver blood test results. Your healthcare provider will do blood tests to check your liver function before you start treatment, and during treatment. Tell your healthcare provider right away if you develop any signs and symptoms of liver problems, including:
  • your skin or the white part of your eyes turns yellow
  • dark or “tea colored” urine
  • light-colored stools (bowel movements)
  • confusion
  • tiredness
  • loss of appetite for several days or longer
  • nausea and vomiting
  • pain, aching, or tenderness on the right side of your stomach-area (abdomen)
  • weakness
  • swelling in your stomach-area

    • The most common side effects include:

  • swelling in your face or other parts of your body
  • tiredness
  • nausea
  • diarrhea
  • muscle and joint pain
  • shortness of breath

    • Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment if you develop serious side effects during treatment. These are not all of the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Tepmetko

    Tell your healthcare provider about all of your medical conditions, including if you:

  • have or have had lung or breathing problems other than your lung cancer
  • have or have had liver problems
  • are pregnant or plan to become pregnant. Tepmetko can harm your unborn baby. Females who are able to become pregnant:
  • Your healthcare provider may do a pregnancy test before you start treatment.
  • You should use effective birth control (contraception) during treatment and for 1 week after the final dose. Talk to your healthcare provider about birth control methods that may be right for you.

    • Males with female partners who are able to become pregnant should use effective birth control during treatment, and for 1 week after the final dose.

  • are breastfeeding or plan to breastfeed. It is not known if Tepmetko passes into your breast milk. Do not breastfeed during treatment and for 1 week after the final dose.

    • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

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    How to use Tepmetko

  • Take Tepmetko exactly as your healthcare provider tells you to.
  • Take Tepmetko 1 time a day with food.
  • Swallow the tablets whole. Do not chew, crush or split tablets.
  • Take your dose of Tepmetko at about the same time each day.
  • Do not change your dose or stop treatment unless your healthcare provider tells you to.
  • If you miss a dose, take it as soon as you remember. If your next dose is due within 8 hours, skip the missed dose and take your next dose at your regular scheduled time.
  • If you vomit after taking a dose, take your next dose at your regular scheduled time.

    • Warnings

     Tepmetko may cause serious side effects, including:

  • Lung problems. Tepmetko may cause severe or life-threatening swelling (inflammation) of the lungs during treatment that can lead to death. Tell your healthcare provider right away if you develop any new or worsening symptoms of lung problems, including:
  • trouble breathing
  • shortness of breath
  • cough
  • fever

    • See Tepmetko side effects for more information about side effects.

    What other drugs will affect Tepmetko

    Other drugs may interact with Tepotinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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