Teriparatide

Generic name: Teriparatide
Brand names: Forteo
Dosage form: subcutaneous solution (620 mcg/2.48 mL)
Drug class: Parathyroid hormone and analogs

Usage of Teriparatide

Teriparatide is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. teriparatide is for use when you have a high risk of bone fracture due to osteoporosis.

Teriparatide may also be used for purposes not listed in this medication guide.

Teriparatide side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Teriparatide may cause serious side effects. Call your doctor at once if you have:

  • bone pain;
  • new or unusual swelling or lumps under your skin;
  • a light-headed feeling, like you might pass out (may occur within 4 hours after injection);
  • pounding heartbeats or fluttering in your chest after using an injection; or
  • high calcium levels--confusion, muscle weakness, nausea, vomiting, lack of energy, constipation, increased thirst or urination, weight loss.
  • Common side effects of teriparatide may include:

  • nausea;
  • joint pain; or
  • pain anywhere in your body.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Teriparatide

    You should not use teriparatide if you are allergic to it.

    Teriparatide is not for use in children or young adults whose bones are still growing.

    Tell your doctor if you have ever had:

  • Paget's disease or a bone disease other than osteoporosis;
  • bone cancer or radiation treatment;
  • a genetic condition that increases your risk of bone cancer;
  • overactive parathyroid glands;
  • high blood levels of calcium;
  • a painful skin condition caused by too much calcium;
  • kidney failure;
  • a kidney stone; or
  • an autoimmune disorder such as rheumatoid arthritis, lupus, or psoriasis.
  • Tell your doctor if you are pregnant or breastfeeding.

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    How to use Teriparatide

    Usual Adult Dose for Osteoporosis:

    20 mcg suBCutaneously once a day into the thigh or abdominal wall-Duration of Therapy: Lifetime use greater than 2 years should only be considered if fracture risk remains highComments: -This drug is indicated for men and women as described below who are at high risk for fracture or who have failed or are intolerant to other available osteoporosis therapy. -High fracture is defined as history of osteoporotic fracture or multiple risk factors for fracture. -Supplemental calcium and vitamin D should be taken if daily dietary intake is inadequate.Uses: -For the treatment of postmenopausal women with osteoporosis -To increase bone mass in men with primary or hypogonadal osteoporosis -For the treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid (equivalent to prednisone 5 mg/day or greater)

    Warnings

    Avoid smoking cigarettes or drinking alcohol. Smoking or heavy drinking can reduce your bone mineral density, making fractures more likely.

    What other drugs will affect Teriparatide

    Tell your doctor about all your other medicines, especially:

  • digoxin, digitalis.
  • warfarin (Coumadin, Jantoven); or
  • a steroid medicine (such as hydrocortisone, prednisone, methylprednisolone, and others).
  • This list is not complete. Other drugs may affect teriparatide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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