Tindamax

Generic name: Tinidazole
Drug class: Amebicides

Usage of Tindamax

Tindamax is an antibiotic that fights bacteria in the body.

Tindamax is used to treat certain infections caused by bacteria, such as infection of the intestines or vagina. Tindamax is also used to treat certain sexually transmitted infections.

Tindamax is used to treat or giardiasis amebiasis in adults and children at least 3 years old.

Tindamax side effects

Get emergency medical help if you have signs of an allergic reaction to Tindamax (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

fever, chills, body aches, flu symptoms;

numbness, burning pain, or tingly feeling;

a seizure; or

vaginal itching or discharge.

Common Tindamax side effects may include:

nausea, vomiting, loss of appetite, indigestion;

constipation, stomach cramps;

feeling weak or tired;

headache, dizziness; or

a metallic or bitter taste in your mouth;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Tindamax

You should not use Tindamax if you are allergic to tinidazole or metronidazole (Flagyl).

Do not use Tindamax to treat any condition that has not been checked by your doctor.

Do not breastfeed within 72 hours after using Tindamax. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.

To make sure Tindamax is safe for you, tell your doctor if you have:

kidney disease (or if you are on dialysis);

a seizure

epilepsy or other seizure disorder;

a blood cell disorder such as anemia or low platelets; or

a weak immune system.

In animal studies, a medicine similar to tinidazole caused cancer. It is not known whether cancer would occur in humans using tinidazole.

It is not known if tinidazole will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may be harder for a man to get a woman pregnant after using this medicine.

Do not give this medicine to a child without medical advice.

Relate drugs

How to use Tindamax

Usual Adult Dose for Trichomoniasis:

2 g orally once Comments: -Appropriate diagnostic procedures should be used to identify organism. -The patient's sexual partner(s) should be treated with the same dose at the same time to prevent reinfection. -Current guidelines should be consulted for additional information.

Usual Adult Dose for Giardiasis:

2 g orally once.

Usual Adult Dose for Amebiasis:

2 g orally once a day Duration of Therapy: -Intestinal: 3 days -Amebic liver abscess: 3 to 5 days Comments: -This drug is not indicated to treat asymptomatic cyst passage. Some Experts Recommend: 2 g orally once a day Duration of Therapy: -Mild to moderate intestinal disease: 3 days -Severe intestinal and extraintestinal disease: 5 days Comments: -Treatment with a luminal amebicide should follow this 3- or 5-day therapy. -Current guidelines should be consulted for additional information.

Usual Adult Dose for Bacterial Vaginosis:

2 g orally once a day for 2 days OR 1 g orally once a day for 5 days Comments: -Formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, or anaerobic vaginosis -Should rule out other pathogens commonly associated with vulvovaginitis (e.g., T vaginalis, Chlamydia trachomatis, Neisseria gonorrhoeae, Candida albicans, Herpes simplex virus) -Use of this drug in pregnant women has not been studied.

Usual Adult Dose for STD Prophylaxis:

US CDC Recommendations: 2 g orally in a single dose Comments: -Recommended as part of a regimen for prophylaxis after sexual assault -Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Giardiasis:

3 years or older: 50 mg/kg orally once Maximum dose: 2 g/dose.

Usual Pediatric Dose for Amebiasis:

3 years or older: 50 mg/kg orally once a day Maximum dose: 2 g/day Duration of Therapy: -Intestinal: 3 days -Amebic liver abscess: 3 to 5 days Comments: -This drug is not indicated to treat asymptomatic cyst passage. -Limited pediatric data on use beyond 3 days; small number of children treated for 5 days had no additional reported side effects. Close monitoring is recommended when duration of therapy exceeds 3 days. Some Experts Recommend: 3 years or older: 50 mg/kg orally once a day Maximum dose: 2 g/day Duration of Therapy: -Mild to moderate intestinal disease: 3 days -Severe intestinal and extraintestinal disease: 5 days Comments: -Treatment with a luminal amebicide should follow this 3- or 5-day therapy. -Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Trichomoniasis:

Some Experts Recommend: 50 mg/kg orally once Maximum dose: 2 g/dose Comments: -Recommended for trichomoniasis due to T vaginalis -The patient's sexual partner(s) should be treated with the same dose at the same time. -Current guidelines should be consulted for additional information.

Usual Pediatric Dose for STD Prophylaxis:

American Academy of Pediatrics Recommendations: 2 g orally in a single dose Comments: -Recommended as part of a regimen for postpubertal adolescents as prophylaxis after sexual assault; recommended for trichomoniasis and bacterial vaginosis -Current guidelines should be consulted for additional information.

Warnings

You should not use Tindamax if you are in the first 3 months of pregnancy. You should not breast-feed a baby while you are taking Tindamax. However, you may begin nursing again 3 days after you take the last dose. Do not keep any milk you collect with a breast pump while you are taking Tindamax.

Before you take Tindamax, tell your doctor if you have kidney disease (or if you are on dialysis), epilepsy or other seizure disorder, a blood cell disorder such as anemia or low platelets, or a weak immune system.

Take Tindamax for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Tindamax will not treat a viral infection such as the common cold or flu. Do not drink alcohol while taking this medicine and for at least 3 days after your treatment ends.

A medicine similar to tinidazole has caused cancer in laboratory animals. It is not known if tinidazole would have the same effect in animals, or in humans. Talk with your doctor about your individual risk.

What other drugs will affect Tindamax

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines. Many drugs can interact with tinidazole, especially:

disulfiram (Antabuse, taken within the past 2 weeks);

fluorouracil;

lithium;

seizure medicine - fosphenytoin, phenytoin; or

medicine to prevent organ transplant rejection - cyclosporine, tacrolimus.

This list is not complete and many other drugs may interact with Tindamax. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.