Trulance

Generic name: Plecanatide
Drug class: Guanylate cyclase-C agonists

Usage of Trulance

Trulance is used to treat chronic idiopathic constipation or irritable bowel syndrome with constipation.

Trulance works by activating certain substances within your intestines that help increase fluid secretion and muscle movement.

Trulance also causes changes in the consistency of your stools.

Trulance side effects

Get emergency medical help if you have signs of an allergic reaction to Trulance: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Diarrhea is a common side effect of Trulance.

Stop using this medicine and call your doctor at once if your diarrhea is severe.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Trulance

You should not use Trulance if you are allergic to plecanatide , or if you have:

a blockage in your intestines.

Do not give this medicine to a child younger than 6 years old.

Avoid using Trulance in anyone younger than 18 years old. In animal studies, plecanatide caused severe dehydration leading to death.

Tell your doctor if you are pregnant or breastfeeding.

Relate drugs

How to use Trulance

Usual Adult Dose for Chronic Idiopathic Constipation:

3 mg orally once a day Use: Treatment of chronic idiopathic constipation (CIC)

Usual Pediatric Dose for Chronic Idiopathic Constipation:

-Under Age 6 Years: Contraindicated. -Age 6 to Under 18 Years: Not recommended.

Warnings

You should not use Trulance if you are allergic to plecanatide, or if you have a blockage in your intestines.

Adults who cannot swallow Trulance tablets whole may crush the tablet and mix with applesauce or dissolve the tablet in water before swallowing. Trulance tablets may also be taken with water by adults through a nasogastric or gastric feeding tube.

What other drugs will affect Trulance

Other drugs may interact with plecanatide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Disclaimer

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