Trulicity Pen

Generic name: Dulaglutide
Brand names: Trulicity Pen
Drug class: Incretin mimetics

Usage of Trulicity Pen

Trulicity is an injectable diabetes medicine that helps control blood sugar levels.

Trulicity is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Trulicity is also used to help reduce the risk of serious heart problems such as heart attack or stroke in adults who have type 2 diabetes and heart disease.

Trulicity is not for treating type 1 diabetes.

Trulicity Pen side effects

Stop using Trulicity and get emergency medical help if you have signs of an allergic reaction to Trulicity: hives; difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting;

signs of a thyroid tumor - swelling or a lump in your neck, trouble swallowing, a hoarse voice, or if you feel short of breath;

low blood sugar - headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or

kidney problems - little or no urination, swelling in your feet or ankles, feeling tired or short of breath.

Tell your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while using this medicine and this can lead to kidney failure.

Common Trulicity side effects may include:

nausea, vomiting, stomach pain;

diarrhea; or

loss of appetite.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Trulicity Pen

You should not use Trulicity if you are allergic to dulaglutide, or if you have:

multiple endocrine neoplasia type 2 (tumors in your glands);

a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer); or

diabetic ketoacidosis (call your doctor for treatment).

Tell your doctor if you have ever had:

pancreatitis;

a stomach or intestinal disorder;

gastroesophageal reflux disease (GERD) or slow digestion;

eye problems caused by diabetes (retinopathy);

liver or kidney disease;

if you also use insulin or oral diabetes medicine; or

if you have been sick with vomiting or diarrhea.

In animal studies, Trulicity caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk.

It is not known whether dulaglutide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Trulicity is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Trulicity Pen

Usual Adult Dose for Diabetes Type 2:

Initial dose: 0.75 mg suBCutaneously once a week -Dose may be increased in 1.5 mg increments for additional glycemic control; patients should remain on 3 mg once a week dose for at least 4 weeks prior to increasing dose to 4.5 mg once a week Maintenance dose: 0.75 to 4.5 mg subcutaneously once a week Maximum dose: 4.5 mg weekly Comments: -This drug should not be used in patients with type 1 diabetes mellitus. -This drug has not been studied in patients with severe gastrointestinal disease, including severe gastroparesis and is not recommended in these patients. -This drug has not been studied in patients with a history of pancreatitis; consider other antidiabetic therapies in these patients. Uses: -As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. -To reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with type 2 diabetes mellitus who have established cardiovascular disease or multiple cardiovascular risk factors.

Usual Adult Dose for Cardiovascular Risk Reduction:

Initial dose: 0.75 mg subcutaneously once a week -Dose may be increased in 1.5 mg increments for additional glycemic control; patients should remain on 3 mg once a week dose for at least 4 weeks prior to increasing dose to 4.5 mg once a week Maintenance dose: 0.75 to 4.5 mg subcutaneously once a week Maximum dose: 4.5 mg weekly Comments: -This drug should not be used in patients with type 1 diabetes mellitus. -This drug has not been studied in patients with severe gastrointestinal disease, including severe gastroparesis and is not recommended in these patients. -This drug has not been studied in patients with a history of pancreatitis; consider other antidiabetic therapies in these patients. Uses: -As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. -To reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with type 2 diabetes mellitus who have established cardiovascular disease or multiple cardiovascular risk factors.

Warnings

You should not use Trulicity if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer). Do not use this medicine if you are in a state of diabetic ketoacidosis (call your doctor for treatment).

In animal studies, Trulicity caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk.

Call your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.

What other drugs will affect Trulicity Pen

Trulicity can slow your digestion, and it may take longer for your body to absorb any medicines you take by mouth.

Other drugs may interact with dulaglutide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.