Typhoid vaccine (live), oral

Generic name: Typhoid Vaccine (live), Oral
Brand names: Vivotif Berna
Dosage form: oral delayed release capsule (-)
Drug class: Bacterial vaccines

Usage of Typhoid vaccine (live), oral

Typhoid vaccine is used to help prevent this disease in adults and children who are at least 6 years old. Although not part of a routine immunization schedule in the U.S., typhoid vaccine is recommended for:

  • people who travel to area where typhoid fever is common (especially Asia, Africa, and Central or South America);
  • people who live with someone who is a typhoid carrier; and
  • laboratory workers who may come into contact with Salmonella typhi in a work setting.
  • This vaccine works by exposing you to a small amount of the bacteria, which causes your body to develop immunity to the disease.

    Typhoid vaccine will not treat an active infection that has already developed in the body, and will not prevent any disease caused by bacteria other than Salmonella typhi.

    Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.

    Typhoid vaccine (live), oral side effects

    Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

    Becoming infected with typhoid fever is much more dangerous to your health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is extremely low.

    Common side effects include:

  • fever;
  • headache;
  • nausea, vomiting, diarrhea, stomach pain; or
  • skin rash.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

    Before taking Typhoid vaccine (live), oral

    You should not receive this vaccine if you have ever had an allergic reaction to typhoid vaccine in the past, or if you have:

  • a fever with any type of infection or illness; or
  • weak immune system caused by disease or by using certain medicine.
  • If you have any of these other conditions, your vaccine may need to be postponed or not given at all:

  • stomach flu or any illness with vomiting or diarrhea;
  • if you are taking an antibiotic, especially a sulfa drug; or
  • if you plan to start taking anti-malaria medicine within 10 days after receiving a typhoid oral vaccine.
  • You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.

    Tell your doctor if you are pregnant or breastfeeding.

    Relate drugs

    How to use Typhoid vaccine (live), oral

    Usual Adult Dose for Typhoid Prophylaxis:

    1 capsule orally, on days 1, 3, 5, and 7, 1 hour before a meal, with cold or lukewarm fluidsComments:-The course should be completed at least 1 week before potential exposure to S. typhi.-Efficacy has been shown to persist for at least 5 years-Routine immunization is not recommended.-Immunization is recommended for travelers to areas with a recognized risk, persons with close exposure to a S. typhi carrier, and laboratory workers who work frequently with S. typhi.

    Usual Pediatric Dose for Typhoid Prophylaxis:

    6 years and older:1 capsule orally, on days 1, 3, 5, and 7, 1 hour before a meal, with cold or lukewarm fluidsComments:-The course should be completed at least 1 week before potential exposure to S. typhi.-Efficacy has been shown to persist for at least 5 years-Routine immunization is not recommended.-Immunization is recommended for travelers to areas with a recognized risk, persons with close exposure to a S. typhi carrier, and laboratory workers who work frequently with S. typhi.

    Warnings

    Tell your doctor if you use other medicines or have other medical conditions or allergies.

    What other drugs will affect Typhoid vaccine (live), oral

    Before using this vaccine, tell your doctor about all other vaccines you have recently received.

    You should not take an anti-malaria medicine that contains proguanil (such as Malarone) for at least 10 days after you have received your last dose of typhoid vaccine. Proguanil may make typhoid vaccine less effective.

    Other drugs may affect typhoid vaccine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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