Tyrvaya

Generic name: Varenicline Solution
Dosage form: nasal spray (0.03 mg per spray)
Drug class: Cholinergic agonists

Usage of Tyrvaya

Tyrvaya nasal spray is used to treat dry eye disease. Tyrvaya increases natural tear production by activating the trigeminal nerves within the nose to relieve dry eye symptoms.

Dry eye disease is often a long-term condition where there are problems with the tear film that normally protects and lubricated the eyes. Dry eye disease causes symptoms of stinging, scratching, burning sensations, sensitivity to light, blurred vision, and eye fatigue, and it may lead to inflammation and damage to the cornea. Natural tears are a complex mixture of proteins, growth factors, and antibodies. Tyrvaya is used to increase the amount of natural tear film to improve the symptoms of dry eye.

Tyrvaya (varenicline solution) is a highly selective cholinergic agonist (mode of action). Tyrvaya became an FDA-approved medicine on Oct. 18, 2021.

Tyrvaya side effects

Common Tyrvaya side effects may include sneezing (82%), cough (16%), throat (13%), and nose irritation (8%). Most side effects reported were mild, and less than 2% of patients stopped treatment in clinical trials due to side effects.

These are not the only possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Tyrvaya

Before using this medicine tell your doctor or prescriber about your medical conditions.

Pregnancy Tell your healthcare provider if you are pregnant, planning a pregnancy, or become pregnant. It is not known if Tyrvaya will harm your unborn baby.

Breastfeeding

Tell your healthcare provider if you are breastfeeding or are planning to breastfeed. It is not known if Tyrvaya passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with this medicine.

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How to use Tyrvaya

Usual Nasal Spray dose:

Use one spray in each nostril twice daily (approximately 12 hours apart).

What other drugs will affect Tyrvaya

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

Disclaimer

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