Ubrelvy

Generic name: Ubrogepant
Dosage form: 50mg tablet, 100mg tablet
Drug class: CGRP inhibitors

Usage of Ubrelvy

Ubrelvy tablets are used to treat migraine headaches in adults, that are with or without aura. Ubrelvy works by blocking a protein called CGRP in the nerve endings that are involved in pain and migraines, this helps reduce pain and migraine symptoms. Ubrelvy is from the CGRP inhibitor class of medicines and is a prescription medicine.

Ubrelvy is used when you have a migraine headache, it is not used to prevent a migraine headache.

Ubrelvy (Ubrogepant) received FDA approval on December 23, 2019, for the acute treatment of migraine with or without aura in adults. They are available as Ubrelvy 100mg tablets and Ubrelvy 50mg tablets.

Ubrelvy side effects

Common Ubrelvy side effects may include nausea or sleepiness.

Serious Ubrelvy side effects Get emergency medical help if you have signs of an allergic Reaction to Ubrelvy: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Ubrelvy

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with Ubrelvy. Your doctor may change your treatment plan if you also use:

Nefazodone;

an antibiotic - clarithromycin, Telithromycin;

antifungal medicine - itraconazole, ketoconazole; or

antiviral medicine to treat HIV/AIDS - Indinavir, Nelfinavir, ritonavir, Saquinavir.

To make sure this medicine is safe for you, tell your doctor if you have:

liver disease; or

kidney disease.

Ubrelvy is not approved for use by anyone younger than 18 years old.

Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Ubrelvy will harm an unborn baby. However, having migraine headaches during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating migraines may outweigh any risks to the baby.

Breastfeeding

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risks.

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How to use Ubrelvy

Usual Adult Dose for Migraine: Take 50 mg to 100 mg orally once, then after 2 hours, a second dose may be taken if needed. Maximum dose: 200 mg in a 24-hour period Comments: The safety of treating more than 8 migraines in a 30-day period is unknown.

Warnings

You should not take Ubrelvy if you are taking medicines known as strong CYP3A4 Inhibitors, such as:

ketoconazole

clarithromycin

itraconazole

Ask your healthcare provider if you are not sure if you are taking any of these medicines. Your healthcare provider can tell you if it is safe to take Ubrelvy with other medicines.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

What other drugs will affect Ubrelvy

Sometimes it is not safe to use certain medications at the SAMe time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines. Many drugs can interact with Ubrelvy, especially:

curcumin (also called turmeric);

cyclosporine;

Eltrombopag;

fluconazole;

fluvoxamine;

phenytoin;

St. John's wort;

an antibiotic - ciprOfloxacin, rifampin;

a barbiturate - bUTAbarbital, phenobarbital, secobarbital; or

heart or blood pressure medicine - Carvedilol, Quinidine, verapamil.

This list is not complete and many Other drugs may interact with ubrogepant. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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