Vibegron

Generic name: Vibegron
Brand names: Gemtesa
Dosage form: oral tablet
Drug class: Urinary antispasmodics

Usage of Vibegron

Vibegron is a type of drug called a beta-3 agonist. It is used to treat overactive bladder. Overactive bladder is a condition which causes a frequent and sudden urge to urinate that is hard to control.

Vibegron works by activating beta-3 adrenergic receptors in the bladder. This relaxes the main muscle in the bladder wall - the detrusor smooth muscle - while the bladder is filling. Relaxation of the detrusor smooth muscle allows you to hold more urine in your bladder, which helps to treat the symptoms of overactive bladder

Vibegron was approved by the US Food and Drug Administration (FDA) in December 2020 and launched under the brand name Gemtesa the following year.

Vibegron side effects

Vibegron may cause serious side effects including:

inability to empty your bladder (urinary retention). Vibegron may increase your chances of not being able to empty your bladder, especially if you have bladder outlet obstruction or take other medicines for treatment of overactive bladder. Tell your doctor right away if you are unable to empty your bladder.

The most common side effects of vibegron include:

urinary tract infection

headache

nasal congestion, sore throat or runny nose

diarrhea

nausea

upper respiratory tract infection

These are not all the possible side effects of vibegron. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Vibegron

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if vibegron will harm your unborn baby.

Tell your doctor if your are breastfeeding or plan to breastfeed. It is not known if vibegron passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take vibegron.

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How to use Vibegron

The recommended dose of vibegron is one 75 mg tablet once daily.

See full prescribing information for more information about vibegron dosing.

What other drugs will affect Vibegron

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your doctor if you take medicines that contain digoxin. Your blood levels of digoxin should be monitored before, during and after treatment with vibegron because treatment with vibegron may affect the dose of digoxin you should take.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

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