Von Willebrand factor recombinant

Generic name: Von Willebrand Factor (recombinant)
Dosage form: intravenous powder for injection (recombinant)
Drug class: Miscellaneous coagulation modifiers

Usage of Von Willebrand factor recombinant

Von Willebrand factor is a naturally occurring protein in the blood that helps blood to clot. People with an inherited blood-clotting disorder called von Willebrand disease do not have enough of this protein in their blood. A lack of von Willebrand factor can cause uncontrolled bleeding.

Von Willebrand factor is used to control bleeding episodes in adults with von Willebrand disease.

Von Willebrand factor may also be used for purposes not listed in this medication guide.

Von Willebrand factor recombinant side effects

Get emergency medical help if you have signs of an allergic reaction: hives, itching; tightness in your throat or chest, difficult breathing; swelling of your face, lips, tongue, or throat.

Von Willebrand factor may cause serious side effects. Call your doctor at once if you have:

  • sudden numbness or weakness (especially on one side of the body);
  • chest pain or pressure, sudden cough, wheezing, rapid breathing, coughing up blood;
  • pain, swelling, warmth, or redness in one or both legs;
  • nausea; or
  • a light-headed feeling, like you might pass out.
  • Common side effects of von Willebrand factor may include:

  • a burning sensation around the IV needle;
  • dizziness, nausea;
  • muscle twitching;
  • unusual or unpleasant taste in the mouth;
  • hot flashes;
  • fast heart rate;
  • itching;
  • chest discomfort; or
  • increased blood pressure.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Von Willebrand factor recombinant

    You should not use von Willebrand factor if you have ever had a severe allergic reaction to von Willebrand factor, or if you are allergic to mice or hamsters.

    To make sure von Willebrand factor is safe for you, tell your doctor if you have ever been told that you have:

  • inhibitors to von Willebrand factor; or
  • inhibitors to blood coagulation factor VIII.
  • It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    It is not known whether von Willebrand factor passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

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    Warnings

    Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

    What other drugs will affect Von Willebrand factor recombinant

    Other drugs may interact with von Willebrand factor, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

    Disclaimer

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