Vowst

Generic name: Fecal Microbiota Spores, Live-brpk
Dosage form: capsules, for oral use

Usage of Vowst

Vowst is a prescription medicine used in adults to prevent Clostridioides difficile infection (CDI) from coming back after completion of antibiotic treatment for C. difficile infection.

Vowst is an oral microbiome therapeutic consisting of live bacteria. It is manufactured from human fecal matter sourced from qualified donors. 

Vowst works to treat CDI by restoring the microbiome (gut flora) back to a balance that resists Clostridioides difficile colonization and growth.

Vowst side effects

The most common side effects include:

  • bloated abdomen
  • fatigue
  • constipation
  • chills
  • diarrhea
  • These are not all the possible side effects. Be sure to tell your healthcare provider about any side effect that bothers you or that does not go away. For more information, ask your healthcare provider or pharmacist.

    Call your healthcare provider for medical advice about side effects. You may report side effects to Aimmune Therapeutics, Inc. at 1-833-246-2566 or FDA at 1-800-FDA-1088 or report online to www.fda.gov/medwatch.

    Before taking Vowst

    Before you take Vowst, read the information provided and make sure you understand it. If you have questions or experience any side effects, talk to your healthcare provider. 

    How to use Vowst

    Usual Adult Dose for Prevention of Recurrence of Clostridioides Difficile Infection (CDI)

    4 capsules taken orally once daily for 3 consecutive days.

    Comments: -Prior to taking the first dose: Complete antibacterial treatment for rCDI 2 to 4 days before initiating treatment with Vowst. Drink 296 mL (10 oz) of magnesium citrate on the day before and at least 8 hours prior to taking the first dose. Take each dose (4 capsules) on an empty stomach prior to the first meal of the day.

    Use:  - to prevent the recurrence of Clostridioides difficile infection (CDI) in individuals 18 years of age and older following antibacterial treatment for recurrent CDI (rCDI).

    What other drugs will affect Vowst

    Vowst should not be taken at the same time as antibiotics.

    Antibiotics can interfere with the live bacteria contained in Vowst.

    Disclaimer

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