Vutrisiran

Generic name: Vutrisiran
Brand names: Amvuttra
Dosage form: subcutaneous solution (25 mg/0.5 mL)
Drug class: Miscellaneous metabolic agents

Usage of Vutrisiran

Vutrisiran is used to treat adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis (damage of multiple nerves throughout the body).

Vutrisiran may also be used for purposes not listed in this medication guide.

Vutrisiran side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Vutrisiran may cause serious side effects. Call your doctor at once if you have:

vision problems (especially at night); or

dryness of the membrane that lines the eyelids and covers the white part of the eye and cornea (the clear layer in front of the iris and pupil).

Common side effects of vutrisiran may include:

pain in your hands or feet;

joint pain;

trouble breathing; or

abnormal blood test.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Vutrisiran

Before using vutrisiran tell your doctor about all your medical conditions or allergies.

Vutrisiran may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using vutrisiran.

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How to use Vutrisiran

Usual Adult Dose for Hereditary Amyloidosis:

Recommended dose: 25 mg administered by suBCutaneous injection once every 3 monthsUse: Treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What other drugs will affect Vutrisiran

Other drugs may affect vutrisiran, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

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