Xelstrym

Generic name: Dextroamphetamine
Drug class: CNS stimulants

Usage of Xelstrym

Xelstrym (Dextroamphetamine) is a central nervous system (CNS) stimulant prescription medicine.

Xelstrym skin patches are used to treat attention deficit hyperactivity disorder (ADHD) in adults and children at least 6 years old.

Xelstrym may help increase attention and decrease impulsiveness and hyperactivity in adults and children 6 years of age and older with ADHD.

Xelstrym is a controlled substance as it contains dextroamphetamine. Xelstrym can be a target for people who abuse prescription medicines or street drugs. Keep the patches in a safe place to protect them from theft. Never give Xelstrym patches to anyone else, as it may cause death or harm them.

Xelstrym side effects

Get emergency medical help if you have signs of an allergic Reaction to Xelstrym (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stimulants have caused stroke, heart attack, and sudden death in certain people. Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, or feeling short of breath.

Xelstrym may cause serious side effects. Call your doctor at once if you have:

  • signs of heart or blood circulation problems - chest pain, trouble breathing, numbness, cold feeling, or pale appearance of your fingers or toes;
  • signs of mania or psychosis - seeing or hearing things that are not real, aggression, paranoia, decreased need for sleep, risk-taking behavior, being agitated or talkative;
  • a seizure, muscle twitches (tics), changes in your vision, blurry vision; or
  • mild skin irritation where the patch is worn.
  • Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

    Dextroamphetamine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

    Common Xelstrym side effects may include:

  • dry mouth, upset stomach, loss of appetite, weight loss;
  • headache, dizziness, sleep problems (insomnia), irritability, muscle twitching (tics); or
  • nausea, vomiting, increased blood pressure, tremors, fast heartbeats.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Xelstrym

    You should not use Xelstrym patches if you are allergic to any stimulant medicine, or if you have:

  • moderate to severe high blood pressure, heart problems or coronary artery disease (clogged arteries);
  • overactive thyroid, glaucoma;
  • severe anxiety, tension, or agitation (stimulant medicine can make these symptoms worse); or
  • a history of drug or alcohol addiction.
  • Do not use Xelstrym if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

    Tell your doctor if you also use opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with dextroamphetamine could cause a serious condition called serotonin syndrome.

    To make sure Xelstrym is safe for you, tell your doctor if you or a family member have ever HAD:

  • a heart defect, high blood pressure, a family history of heart disease or sudden death;
  • depression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions;
  • motor tics (muscle twitches) or Tourette's syndrome;
  • seizures or epilepsy, an abnormal brain wave test (EEG);
  • contact dermatitis;
  • blood circulation problems or peripheral vascular disease such as Raynaud's syndrome; or
  • kidney disease.
  • Tell your doctor if you are pregnant or plan to become pregnant. Using Xelstrym during pregnancy may increase the risk of premature birth, withdrawal symptoms or low birth weight.

    If you are pregnant, your name may be listed on a pregnancy registry to track the effects of dextroamphetamine skin patch on the baby.

    You should not breastfeed while using Xelstrym.

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    How to use Xelstrym

    Pediatric Patients. Recommended starting dose in pediatric patients 6 to 17 years: 4.5 mg /9 hours. DoSage may be adjusted in weekly increments of 4.5 mg up to a maximum recommended dose of 18 mg/9 hours.

    Adults. Recommended starting dose: 9 mg/9 hours. Dosage may be adjusted up to a maximum recommended dose of 18 mg/9 hours.

    Warnings

    You should not use Xelstrym skin patches if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, or a history of drug or alcohol addiction.

    Dextroamphetamine may be habit-forming. Misuse can cause addiction, serious heart problems, or death.

    Call your doctor right away if you have: chest pain, seeing or hearing things that are not real, decreased need for sleep, being agitated, unexplained wounds on your fingers or toes.

    What other drugs will affect Xelstrym

    Sometimes it is not safe to use certain medicines at the SAMe time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

    Tell your doctor about all your current medicines. Many drugs can interact with dextroamphetamine, especially:

  • an antacid, migraine headache medicine, seizure medicine;
  • Fentanyl, tramadol, lithium, Buspirone;
  • acetazolamide, tryptophan, methenamine, vitamin c products;
  • an antidepressant, a diuretic or "water pill"; or
  • blood pressure medication.
  • This list is not complete and many other drugs may interact with dextroamphetamine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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