Xyosted

Generic name: Testosterone Injection
Brand names: Xyosted
Drug class: Androgens and anabolic steroids

Usage of Xyosted

Xyosted injection is a single-dose syringe supplied as an autoinjector containing testosterone. Testosterone is a naturally occurring sex hormone produced in a man's testicles.

Xyosted is a prescription medicine used as a hormone replacement therapy in adult men who have low or no testosterone due to certain medical conditions.

Xyosted will not enhance athletic performance and should not be used for that purpose.

It is not known if Xyosted is safe or effective in children younger than 18 years old. Improper use of testosterone may affect bone growth in children.

Xyosted side effects

Get emergency medical help if you have signs of an allergic reaction to Xyosted: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have a tight feeling in your throat, a sudden urge to cough, or if you feel light-headed or short of breath during or shortly after receiving the injection.

You will be watched closely for at least 30 minutes to make sure you do not have a reaction to the injection.

Call your doctor at once if you have:

  • chest pain or pressure, pain spreading to your jaw or shoulder;
  • shortness of breath, breathing problems at night (sleep apnea);
  • swelling in your ankles or feet, rapid weight gain;
  • a seizure;
  • unusual changes in mood or behavior;
  • increased or ongoing erection of the penis, ejaculation problems, decreased amounts of semen, decrease in testicle size;
  • painful or difficult urination, increased urination at night, loss of bladder control;
  • high levels of calcium in the blood - stomach pain, constipation, increased thirst or urination, muscle pain or weakness, joint pain, confusion, and feeling tired or restless; or
  • high potassium level - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;
  • liver problems - right-sided upper stomach pain, vomiting, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes).
  • signs of a blood clot deep in the body - swelling, warmth, or redness in an arm or leg;
  • signs of a blood clot in the lung - chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or
  • signs of a stroke - sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems.
  • Your Xyosteds may be delayed or permanently discontinued if you have certain side effects.

    Common Xyosted side effects may include:

  • breast swelling;
  • acne, increased facial or body hair growth, male-pattern baldness;
  • increased or decreased interest in sex;
  • headache, anxiety, depressed mood;
  • increased blood pressure;
  • numbness or tingly feeling;
  • abnormal liver function tests;
  • high red blood cell counts (hematocrit or hemoglobin);
  • increased PSA (prostate-specific antigen); or
  • pain, bruising, bleeding, redness, or a hard lump where the medicine was injected.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Xyosted

    You should not be treated with Xyosted if you are allergic to testosterone, or if you have:

  • male breast cancer;
  • prostate cancer;
  • serious heart problems;
  • severe liver disease;
  • severe kidney disease; or
  • an allergy to castor oil or sesame oil.
  • Xyosted is not for use in women. This medicine can harm an unborn baby.

    To make sure Xyosted is safe for you, tell your doctor if you have ever had:

  • high blood pressure;
  • heart problems, coronary artery disease (clogged arteries);
  • a heart attack or stroke;
  • sleep apnea;
  • an enlarged prostate and urination problems;
  • high cholesterol or triglycerides;
  • cancer;
  • depression, anxiety, a mood disorder, suicidal thoughts or actions;
  • diabetes;
  • high red blood cell (RBC) counts; or
  • liver or kidney disease.
  • Using Xyosted may increase your risk of developing prostate cancer, liver problems, or heart problems (including heart attack, stroke, or death). Ask your doctor about these risks.

    Xyosted should not be given to a child younger than 12 years old. Some types of this medicine are not approved for use by anyone younger than 18 years old.

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    How to use Xyosted

    Xyosted is injected under the skin or into a muscle, usually given every 2 to 4 weeks. Xyosteds should be given only by a healthcare professional.

    Testosterone can raise your blood pressure, which could increase your risk of heart attack, stroke, or death. Your blood pressure will need to be checked often. You may need to stop using Xyosted or start taking blood pressure medication.

    You will need frequent blood tests.

    Testosterone can affect the results of certain medical tests. Tell any doctor who treats you that you are using Xyosted.

    Misuse of Xyosted can cause dangerous or irreversible effects, such as enlarged breasts, small testicles, infertility, high blood pressure, heart attack, stroke, liver disease, bone growth problems, addiction, and mental effects such as aggression and violence. Stealing, selling, or giving away this medicine is against the law.

    If you have used too much Xyosted, stopping the medicine may caused unpleasant withdrawal symptoms, such as depression, tiredness, irritability, loss of appetite, sleep problems, or decreased libido.

    Warnings

    You should not be treated with Xyosted if you have prostate cancer, male breast cancer, a serious heart condition, severe liver or kidney disease, or an allergy to castor oil or sesame oil.

    Xyosted is not for use in treating low testosterone without certain medical conditions or due to getting older. Testosterone should not be used to enhance athletic performance.

    Xyosted is not for use in women.

    Testosterone can increase your risk of heart attack, stroke, or death. You may need to stop using Xyosted or start taking blood pressure medication.

    Misuse of testosterone can cause dangerous or irreversible effects. Do not share this medicine with another person.

    What other drugs will affect Xyosted

    Tell your doctor about all your other medicines, especially:

  • insulin or oral diabetes medicine;
  • medicine to treat pain, cough, or cold symptoms;
  • a blood thinner - warfarin, Coumadin, Jantoven; or
  • steroid medicine - prednisone, dexamethasone, and others.
  • This list is not complete. Other drugs may interact with testosterone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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