Zoloft
Generic name: Sertraline
Drug class:
Selective serotonin reuptake inhibitors
Usage of Zoloft
Zoloft is an antidepressant that belongs to a group of drugs called selective serotonin reuptake inhibitors (SSRIs), which works by balancing serotonin levels in the brain and nerves. Zoloft is used to treat some types of depression, premenstrual dysphoric disorder (PMDD), social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), panic disorder (PD), and post traumatic stress disorder (PTSD).
Zoloft side effects
Get emergency medical help if you have signs of an allergic reaction to Zoloft: skin rash or hives (with or without fever or joint pain); difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Zoloft may cause serious side effects. Call your doctor at once if you have:
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Sertraline can affect growth in children. Your child's height and weight may be checked often.
Common side effects of Zoloft may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Zoloft
You should not use Zoloft if you are allergic to sertraline, or if you also take pimozide. Do not use Zoloft oral solution if you take disulfiram (Antabuse).
Do not use Zoloft if you have used an MAO inhibitor in the past 14 days.. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine. Wait at least 14 days after stopping an MAO inhibitor before you take Zoloft ..
Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with sertraline could cause a serious condition called serotonin syndrome.
To make sure Zoloft is safe for you, tell your doctor if you have ever had:
Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Your doctor will need to check your progress on a regular basis. Your family or caregivers should also watch for sudden changes in your behavior.
Zoloft is approved for use in children at least 6 years old, only to treat obsessive-compulsive disorder but not depression.
Taking this medicine during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop Zoloft without asking your doctor.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of sertraline on the baby.
Ask a doctor if it is safe to breastfeed while using Zoloft .
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How to use Zoloft
Usual Adult Dose for Depression:
Initial dose: 50 mg orally once a day Maintenance Dose: 50 to 200 mg orally once a day.
Usual Adult Dose for Obsessive Compulsive Disorder:
Initial dose: 50 mg orally once a day Maintenance Dose: 50 to 200 mg orally once a day.
Usual Adult Dose for Panic Disorder:
Initial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day Maintenance dose: 50 to 200 mg orally once a day.
Usual Adult Dose for Post Traumatic Stress Disorder:
Initial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day Maintenance dose: 50 to 200 mg orally once a day.
Usual Adult Dose for Social Anxiety Disorder:
Initial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day Maintenance dose: 50 to 200 mg orally once a day.
Comments: -Dose adjustments may be made at intervals of at least one week. -These conditions generally required several months or longer of sustained pharmacological therapy beyond initial treatment.
Usual Adult Dose for Premenstrual Dysphoric Disorder:
Continuous regimen: -Initial dose: 50 mg orally once a day during the menstrual cycle -Maintenance dose: 50 to 150 mg orally once a day during the menstrual cycle Cyclic regimen: -Initial dose: 50 mg orally once a day starting 14 days prior to the anticipated start of menstruation through to the first full day of menses, and repeated with each new cycle -Maintenance dose: 50 to 100 mg orally once a day.
Comments: -The dose may be increased in increments of 50 mg per menstrual cycle, increased at the onset of each new cycle; dosage adjustments may also include changes between regimens. -If a 100 mg once daily dose has been established with the cyclic regimen, a titration step of 50 mg per day for three days should be used at the beginning of each dosing period (luteal phase of the menstrual cycle). -The effectiveness of Zoloft for longer than three months has not been systematically evaluated in controlled trials.
Usual Pediatric Dose for Obsessive Compulsive Disorder:
6 to 12 years: -Initial dose: 25 mg orally once a day -Maintenance dose: 25 to 200 mg orally once a day 13 to 17 years: -Initial dose: 50 mg orally once a day -Maintenance dose: 50 to 200 mg orally once a day.
Comments: -The dose may be increased at intervals of at least one week. -The potential risks versus clinical need should be assessed prior to using this drug in children and adolescents.
Warnings
Do not stop taking Zoloft without your doctor's advice.
People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
What other drugs will affect Zoloft
Zoloft can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.
Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, naproxen, Advil, Aleve, Motrin, and others. Using an NSAID with Zoloft may cause you to bruise or bleed easily.
Other drugs may interact with sertraline, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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