Zolpidem
Generic name: Zolpidem
Drug class:
Miscellaneous anxiolytics , Antineoplastic Agents
Usage of Zolpidem
Zolpidem is used in adults to treat insomnia.
The immediate-release forms are Ambien, Edluar, and Zolpimist, which are used to help you fall asleep. Intermezzo, is used to help you fall back to sleep if you wake up in the middle of the night and then have trouble sleeping. The extended-release form of zolpidem is Ambien CR which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep.
Your doctor will determine which form of zolpidem is best for you.
Zolpidem belongs to a class of medications called sedative-hypnotics. It works by slowing activity in the brain to allow sleep.
Zolpidem side effects
Get emergency medical help if you have signs of an allergic reaction to zolpidem: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some people using zolpidem have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity. If this happens, stop using zolpidem and call your doctor right away.
Serious injury or death could occur if you walk or drive while you are not fully awake.
Zolpidem may cause serious side effects. Call your doctor at once if you have:
Common zolpidem side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Zolpidem
You should not use zolpidem if you are allergic to it, or if you have ever taken sleep medicine and engaged in activity you later don't remember.
Zolpidem may contain lactose. Tell your doctor if you have galactose intolerance, or severe problems with lactose (milk sugar).
To make sure zolpidem is safe for you, tell your doctor if you have ever had:
Tell your doctor if you are pregnant or plan to become pregnant. Using this medicine during the last 3 months of pregnancy may harm the unborn baby.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of zolpidem on the baby.
Ask a doctor if it is safe to breastfeed while using this medicine.
If you are breastfeeding, tell your doctor if you notice increased sleepiness, breathing problems, or limpness in the nursing baby.
Do not breastfeed within 23 hours after using zolpidem. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.
Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury.
Relate drugs
- Ambien
- Ambien CR
- Belsomra
- Buspar
- Buspar Dividose
- Buspirone
- Calcium oxybate, magnesium oxybate, potassium oxybate, and sodium oxybate
- Calcium, magnesium, potassium, and sodium oxybates
- Daridorexant
- Dayvigo
- Dexmedetomidine (Intravenous)
- Dexmedetomidine (Oromucosal)
- Dexmedetomidine buccal/sublingual
- Dexmedetomidine injection
- Doxylamine
- Edluar
- Eszopiclone
- Ethchlorvynol
- Hetlioz
- Hetlioz LQ
- Igalmi buccal/sublingual
- Intermezzo
- Lemborexant
- Lumryz
- Lunesta
- Mb-Tab
- Meprobamate
- Miltown
- Natrol Melatonin + 5-HTP
- Paraldehyde
- Placidyl
- Precedex
- Precedex injection
- Quviviq
- Ramelteon
- Rozerem
- Sodium oxybate
- Sonata
- Suvorexant
- Tasimelteon
- Trancot
- Unisom
- Vanspar
- Xyrem
- Xywav
- Zaleplon
- Zolpidem
- Zolpidem (Oral)
- Zolpidem (Oromucosal, Sublingual)
- ZolpiMist
- 5-hydroxytryptophan, melatonin, and pyridoxine
How to use Zolpidem
Usual Adult Dose for Insomnia:
IMMEDIATE RELEASE (IR) TABLETS, ORAL SPRAY, and SUBLINGUAL TABLETS (5 and 10 mg formulations): Initial dose: -Women: 5 mg orally once a day immediately prior to bedtime -Men: 5 to 10 mg orally once a day immediately prior to bedtime Maintenance dose: 5 to 10 mg orally once a day immediately prior to bedtime Maximum dose: 10 mg/day CONTROLLED/EXTENDED RELEASE (CR/ER) TABLETS: Initial dose: -Women: 6.25 mg orally once a day immediately prior to bedtime -Men: 6.25 to 12.5 mg orally once a day immediately prior to bedtime Maintenance dose: 6.25 to 12.5 mg orally once a day immediately prior to bedtime Maximum dose: 12.5 mg/day SUBLINGUAL TABLETS (1.75 and 3.5 mg Formulations): Women: 1.75 mg orally once a day at night as needed -Maximum dose: 1.75 mg/day Men: 3.5 mg orally once a day at night as needed -Maximum dose: 3.5 mg/day Comments: -The recommended initial doses for women and men are different due to the lower rate of drug clearance in females. -Clinical trials supporting IR tablet efficacy were 4 to 5 weeks' duration, while CR/ER tablet efficacy were 3 to 24 weeks in duration. -The 1.75 and 3.5 mg sublingual tablet formulations should be taken when the patient wakes in the middle of the night and has trouble falling back to sleep. -LIMITATION OF USE: The 1.75 and 3.5 mg sublingual tablet formulations are not indicated for the treatment of insomnia in patients who have less than 4 hours of bedtime remaining before the planned awakening time. Uses: -IR Tablets, Oral Spray, and Sublingual Tablets (5 and 10 mg Formulations): Short-term treatment of insomnia characterized by difficulties with sleep initiation -CR/ER Tablets: Treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance (as measured by wake time after sleep onset) -Sublingual Tablets (1.75 and 3.5 mg Formulations): As needed for the treatment of insomnia when a middle-of-the-night awakening is followed by difficulty returning to sleep
Usual Geriatric Dose for Insomnia:
IR TABLETS, ORAL SPRAY, and SUBLINGUAL TABLETS (5 and 10 mg formulations): 5 mg orally once a day immediately prior to bedtime -Maximum dose: 5 mg/day CR/ER TABLETS: Patients 65 years and over: 6.25 mg orally once a day at night immediately prior to bedtime -Maximum dose: 6.25 mg/day SUBLINGUAL TABLETS (1.75 and 3.5 mg Formulations): Patients over 65 years: 1.75 mg orally once a day at night as needed -Maximum dose: 1.75 mg/day Comments: -Doses are the same in men and women. -Clinical trials supporting IR tablet efficacy were 4 to 5 weeks' duration, while CR/ER tablet efficacy were 3 to 24 weeks in duration. -The 1.75 sublingual tablet formulations should be taken when the patient wakes in the middle of the night and has trouble falling back to sleep. -LIMITATION OF USE: The 1.75 sublingual tablet formulations are not indicated for the treatment of insomnia in patients who have less than 4 hours of bedtime remaining before the planned awakening time. Uses: -IR Tablets, Oral Spray, and Sublingual Tablets (5 and 10 mg Formulations): Short-term treatment of insomnia characterized by difficulties with sleep initiation -CR/ER Tablets: Treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance (as measured by wake time after sleep onset) -Sublingual Tablets (1.75 and 3.5 mg Formulations): As needed for the treatment of insomnia when a middle-of-the-night awakening is followed by difficulty returning to sleep
Warnings
Never use zolpidem in larger amounts, or for longer than prescribed.
Some people using zolpidem have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity. Tell your doctor if this happens to you.
Zolpidem may cause a severe allergic reaction. Stop taking zolpidem and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Do not share this medication with another person, even if they have the same symptoms you have. The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children. Misuse of this medication can result in dangerous side effects.
Zolpidem may impair your thinking or reactions. You may still feel sleepy the morning after taking this medicine, especially if you take the extended-release tablet, or if you are a woman. Wait at least 4 hours or until you are fully awake before you do anything that requires you to be awake and alert. Serious injury or death could occur if you walk or drive while you are not fully awake.
Never take this medicine in larger amounts or for longer than prescribed.
Do not take zolpidem if you have consumed alcohol during the day or just before bed.
What other drugs will affect Zolpidem
Using zolpidem with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, or seizures.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect zolpidem, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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