Zyban

Generic name: Bupropion
Drug class: Smoking cessation agents

Usage of Zyban

Zyban is used to help people stop smoking by reducing cravings and other withdrawal effects.

Bupropion may also be used for purposes not listed in this medication guide.

Zyban side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Zyban: (hives, itching, fever, swollen glands, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, depression, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

a seizure (convulsions);

confusion, unusual changes in mood or behavior;

blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;

fast or irregular heartbeats; or

a manic episode - racing thoughts, increased energy, reckless behavior, feeling extremely happy or irritable, talking more than usual, severe problems with sleep.

Common Zyban side effects may include:

dry mouth, sore throat, stuffy nose;

ringing in the ears;

blurred vision;

nausea, vomiting, stomach pain, loss of appetite, constipation;

sleep problems (insomnia);

tremors, sweating, feeling anxious or nervous;

fast heartbeats;

confusion, agitation, hostility;

rash;

weight loss;

increased urination;

headache, dizziness; or

muscle or joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Zyban

Do not use Zyban if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not take Zyban if you are allergic to bupropion, or if you have:

a seizure disorder;

an eating disorder such as anorexia or bulimia; or

if you have suddenly stopped using alcohol, seizure medication, or a sedative such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take bupropion. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Zyban to treat more than one condition at a time. If you take Wellbutrin for depression, do not also take this medicine to quit smoking.

Zyban may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor;

narrow-angle glaucoma;

heart disease, high blood pressure, or a heart attack;

diabetes;

kidney or liver disease (especially cirrhosis); or

depression, bipolar disorder or other mental illness; or

if you drink alcohol.

Ask your doctor about taking Zyban if you are pregnant. It is not known whether bupropion will harm an unborn baby. Tell your doctor right away if you become pregnant. Do not start or stop taking bupropion without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Relate drugs

How to use Zyban

Usual Adult Dose for Smoking Cessation:

Initial Dose: 150 mg orally once a day. Maintenance: Based on clinical response, this dosage may be increased to 300 mg/day, given as 150 mg twice a day, no sooner than 3 days after beginning therapy.

Warnings

You should not take Zyban if you have seizures, an eating disorder, or if you have suddenly stopped using alcohol, seizure medication, or sedatives. If you take Wellbutrin for depression, do not also take Zyban to quit smoking.

Do not use bupropion if you have used a MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Zyban may cause seizures, especially in people with certain medical conditions or when using certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Zyban. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

What other drugs will affect Zyban

You may have a higher risk of seizures if you use certain other medicines while taking Zyban.

Many drugs can interact with bupropion. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Zyban. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Disclaimer

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