0.75m DHG Rovas drink powder for respiratory infections, skin (24 packs x 3g)

Dosage form Box of 24 packs x 3g
Specifications Spiramycin

Ingredient

Composition information	Content
Spiramycin	0.75m

Uses

indications

0.75m Rovas drug is indicated in the following cases:

Spiramycin is considered the second choice to treat cases of respiratory, skin, and genital infections caused by drugs that are sensitive to drugs. Acute joints recur in patients with allergies to penicillin. In serum concentrations, the drug has a bactericidal effect, but when the tissue is reached, the drug can kill bacteria. The mechanism of the effect of spiramycin is the effect on the subunit of 50S of bacterial ribosom and preventing protein synthetic bacteria.

Spiramycin has a resistance to Gram -positive strains, coccus strains such as staphylococcus, pneumococcus, meningococcus ...

Dynamic pharmacokinetics

Spiramycin is absorbed completely in the digestive tract. Oral drugs are absorbed about 20-50% of the dose of use. The peak concentration of plasma is achieved within 2-4 hours after drinking. The concentration of peaks in the blood after the single dose can be maintained for 4 to 6 hours.

Take Spiramycin when food in the stomach greatly reduces the bioavailability of the drug. Food reduces about 70% of the maximum concentration of the drug in the serum and makes the peak time from 2 hours.

Spiramycin is widely distributed throughout the body. The drug reaches high concentrations in the lungs, tonsils, bronchial and sinuses. Spiramycin is less penetrated into the cerebrospinal fluid. The average selling time is 5 - 8 hours. The drug is excreted mainly in bile. After 36 hours, only about 2% of the total dose is found in the urine.

Before taking 0.75m DHG Rovas drink powder for respiratory infections, skin (24 packs x 3g)

How to use

oral medication. This drug is only used by a doctor.

Food in the stomach reduces the bioavailability of Spiramycin, so it is necessary to give the medication before meals for at least 2 hours or 3 hours after meals.

Dosage

Dosage treatment

Children and children: take 150,000 IU/kg body/24 hours, divided into 2-3 times.

Or: Children and children under 10 kg: take 1-2 packs/24 hours, divided into 2-3 times.

Children from 10 - 20 kg: take 2 - 4 packs/24 hours, divided into 2-3 times.

Preventive treatment for meningitis caused by meningococcus strains

Children: Take 75,000 IU KG body weight. 1 time to drink 1 time, in 5 days.

Preventive prophylaxis toxoplasma is born during pregnancy: 9,000,000 IU/day, divided into several times for 3 weeks, every 2 weeks for the reminders.

Used in combination or alternating with Pyrimethamine/Sulfonamid treatment regimen can achieve better results.

Patients using Spiramycin must follow the end of the treatment.

or as directed by the physician.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? In case of an overdose, it is required to immediately notify the doctor.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using 0.75m Rovas, you may experience unwanted effects (ADR).

Common

Nausea, vomiting, diarrhea, indigestion (when used oral).

rarely

Systemic: fatigue, nosebleeds, sweating, chest pressing.

Anaphylactic reactions, superinfection due to long -term use of spiramycin oral medication.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Rovas 0.75M is contraindicated for those with a history of hypersensitivity to Spiramycin, erythromycin.

Be cautious when used

Precautions when used for patients with liver dysfunction, because the drug can be toxic to the liver.

The ability to drive and operate machinery

rarely affects the ability to drive and operate machinery.

pregnancy

spiramycin passes through the placenta, but the concentration of drugs in the fetal blood is lower than the mother's blood. Spiramycin does not cause complications when used for pregnant people.

The period of breastfeeding

Spiramycin is excreted through breast milk with high concentrations. Should stop breastfeeding while taking the drug.

Medicinal interaction

use Spiramycin simultaneously with oral contraceptive medicine to prevent conceiving effects.

Storage

Store in dry places, temperatures not exceeding 30 ° C, avoiding light.

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