1% Medipharco 1% Medipharco Eye Mediocyto (5g) treatment (5g)

Dosage form Tube x 5g
Specifications Tetracycline

Ingredient

Composition information	Content
Tetracycline	1%

Uses

indications

1% tetracyclin is indicated in the following cases:

Eye infections caused by Chungmydia: trachoma.

In other eye infections: only tetracycline should be used when the bacteria are still sensitive.

Due to the serious level of resistance of bacteria and there are many other antibacterial drugs, limiting the use of tetracycline in treatment.

Pharmacological

Tetracyclin is a broad -spectrum antibiotic that has the effect of bacteria due to inhibiting bacterial protein synthesis. The mechanism of action of tetracycline is due to the ability to attach and inhibit the ribosom function of bacteria.

When entering bacterial cells, Tetracyclin attaches to the subunit 30s of ribosom, preventing the cohesion of T-RNA aminoacyl T-RNA that inhibits protein synthesis. When tetracyclin resistant bacteria, the position of tetracycline on ribosom is changed. Therefore, tetracycline is not attached to the ribosom of bacteria and ineffective.

basic tetracyclin works on many bacteria that cause both gram -negative and gram -positive bacteria, both aerobic and anaerobic; The drug also works on Chlamydia, Mycoplasma, Rickettsia, and Spirochochete. Mushrooms, yeast, viruses are not sensitive to tetracyclin.

Medicinal resistance mechanism:

The anti -tetracycline mechanism in propionibacteria is often linked to a single mutant point in the 16S RRNA encryption gene. The clinical independent of tetracyclin is found to have cytosine instead of guanine in a position of the same origin as the Escherichia Coli Base 1058. There is no evidence that the mutant ribosome can be transferred between different strains or propionibacteria species, or between propionibacteria and some bacteria on other leather.

resistance to Tetracycline is associated with the factor determining the mobile resistance in both staphylococcus and bacteria Coyneform. This determination factor is potentially capable of transmission between other species and even different from bacteria.

Of all three species, diagonal with macrolide-lincosamide-streptogramin group of antibiotics cannot be removed.

Propionibacteria strains resistant to tetracyclin are diagonal with DoxycyCline and may or may not be able to show reduced sensitivity to minocyclin.

pharmacokinetics

absorption:

Tetracyclin is absorbed through the digestive tract.

Distribution:

Widely distributed in tissues and body fluids. A small amount appears in saliva, tears and fluid. Tetracyclin also appears in breast milk with a concentration that can reach 60% or more than the concentration of medication in the mother's blood.

Tetracyclin through the placenta and appears in the fetal circulation at a concentration of 25 - 75% compared to the concentration of drugs in the mother's blood. Tetracyclin attaches to the bone during the new bone formation, the calcification process and affects the formation of bones and teeth.

Metabolism and elimination:

The drug is discharged in urine in unproperated form. In addition, the drug is also excreted through bile into the intestine and one fertilizer is reabsorbed again through the hepatic circulation. The bactericidal concentration is still maintained for up to 6 hours after use in the form of eye fat.

Before taking 1% Medipharco 1% Medipharco Eye Mediocyto (5g) treatment (5g)

How to use

Use eyes.

Dosage

A small amount of ointment into the eye is sick, 2-3 times/day, avoiding contact with dust after examination.

Treatment time for trachoma from 20 days to 2 months.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? Sometimes edema, irritation or allergic reactions may occur.

If any abnormal manifestation occurs when using the recommended overdose, it is necessary to stop using the drug and immediately notify the doctor or go to the nearest medical facility for examination. It is necessary to keep this user manual, box or tube sample if possible.

Symptoms of overdose include: edema, eye irritation or allergic reaction.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using 1%tetracyclin, you may experience unwanted effects (ADR).

Some unwanted effects may occur when using Tetracyclin eye ointment:

Tears, feelings and eye blur.

tetracyclin can cause excessive growth of unsure microorganisms, including fungi, leading to superinfection.

underdeveloped and discolored young teeth when using tetracyclin for pregnant women and children under 8 years old.

Skin allergic reactions, urticaria, edema, increased sensitivity to light when exposed to direct sunlight.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

1% tetracyclin drug in the following cases:

Sensitive to any ingredients of the drug.

Pregnant women and children under 8 years old, due to the use of tetracyclin drugs during the development of the teeth (the second half of pregnancy and children under 8 years old) can cause permanent teeth color variables (yellow, gray, brown) and the drug can be attached and affect bone growth.

Be cautious when using

before using tetracyclin, the doctor or pharmacist must know if you are allergic to tetracyclin; Or if there is any other allergy. This product contains non -activity components, which can cause allergies.

Some cases of tetracyclin use a sensitive reaction to light manifested by sunburn when exposed to sunlight. Patients use Tetracyclin if exposed to direct sunlight or ultraviolet rays should be warned about this risk and need to stop the drug as soon as the first symptoms of the Red Red Red

Before using 1%tetracyclin eye ointment, it must be given your doctor or pharmacist about your medical history, especially: other eye problems (such as previous eye infections); Use contact lenses.

When used to avoid the tip of the drug rubbing into the eyes.

Close the lid after use, avoiding the pipeline contamination.

The ability to drive and operate machinery

ointment can cause eye blur after use, so wait until the eye blur to drive or operate machinery, do higher work and other cases.

Pregnancy

During pregnancy, the drug should only be used when really necessary. Doctors need to consider when the benefits of superior treatment may occur for the fetus.

The period of breastfeeding

It is not known that the drug has entered the breast milk when used in the form of cool ointment. Therefore, it is necessary to consult a doctor before using the drug.

Interactive drugs

Because the drug is used in the form of eye traces, the interaction between the drug and other drugs is rarely occurring.

If used simultaneously with other drugs should be used for about 30-60 minutes.

Storage

In a dry place, temperatures below 30 ° C, avoid light.

Other drugs

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