2% lidocaine injection solution used for local anesthesia (100 tubes x 2ml)

Dosage form 100 tube box
Specifications Lidocaine

Ingredient

Thành phần cho 2ml

Composition informationContent
Lidocaine40mg

Uses

indicated

Numbness in the mucosa to relieve pain symptoms.

Anesthesia and nervous anesthesia techniques include peripheral anesthesia, sympathetic nodes, epidural anesthesia, cavity anesthesia and spinal anesthesia.

Pharmacological

lidocaine is local anesthetic, amid group, with average time. Lidocaine is anti -arrhythmia, Na channel blockers, group 1B, used intravenously to treat ventricular arrhythmia.

pharmacokinetics

absorption:

After intravenous injection, the first half of the life (8-10 minutes), half -life eliminated at the end (100 - 120 minutes). Lidocaine effect depends on the maintenance of plasma treatment concentrations in the central compartment.

Distribution:

1.1 + 1%. Attached with plasma protein: 70 + 5%. The clearance: 9.2 + 2.4 ml/min/kg. Distribution volume: 1.1 + 0.4 v/kg. The concentration works: 1.5-6 micrograms/ml. Toxic concentration, sometimes: 6-10 mcg/ml, common> 10 mcg/ml.

Before taking 2% lidocaine injection solution used for local anesthesia (100 tubes x 2ml)

How to use

Use topical or injection.

Dosage

Numbness in the nasal mucosa, mouth, throat, bronchial, esophagus and urinary - genital:

Apply 2%Lidocaine solution directly.

Maximum doses of safety for local anesthesia for adults weighing 70kg is 500 mg of lidocaine.

Anesthesia:

Inject directly into the injection tissue (0.5% - 1%); When not adrenalin adds: lidocaine dose up to 4.5 mg/kg; When added adrenalin: This dose may be added to one third (7mg/kg).

Anesthesia:

subcutaneous injection of Lidocaine hydrochloride solution along with concentrations and dosage as anesthetic in each layer.

Neurotic anesthesia:

Inject lidocaine solution in or near the nerve or peripheral nerve puppet that has a wider anesthetic effect than the above techniques.

For 2-4 hours of closing, lidocaine can be used (1%-1.5%) with recommended doses such as class anesthesia.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Expression:

sedation, confusion, coma, convulsions, suspension and toxic heart toxic (sinus stop, atrial block - ventricular, heart failure and lower blood pressure); Normal QRS and Q-T intervals, although it may last for severe overdose. Other effects include dizziness, paresthesia, tremor, loss of air conditioning, and digestive disorders.

Management:

Support by conventional measures (infusion, appropriate posture, hypertension drugs, anti -arrhythmic drugs, anti -convulsions); Sodium bicarbonate can recover long -term QRS, bradycardia and lower blood pressure. Hematopause increases lidocaine elimination.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Common, ADR> 1/100

  • Cardiovascular: lower blood pressure.

    • Central nerve: headache when changing posture. other: Run.

    Uncommon, 1/1000

  • Cardiovascular: heart block, arrhythmia, cardiovascular collapse, cardiac arrest, shortness of breath, decline or respiratory arrest.
    • Mental: Sleeping, coma, excitement, saying, convulsions, anxiety, refreshment, hallucinations, paresthesia. skin: itching, ban, skin edema. immune: numb around the lips and tip of the tongue. digestion: Nausea, vomiting.
  • Eyes: blurred vision.

    • Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Contraindicated

    2% Lidocaine Kabi drug contraindicated in the following cases:

  • Hypersensitivity to amids anesthetic, patients with adams - stokes syndrome or sinus - atrial, atrial - ventricular disorders - ventricular at all levels, severe myocardial failure, or block in ventricular (when there is no rhythmic device), Porphyrin metabolism disorders.
  • Inject anesthetic in inflamed tissues, bacterial infections, injuries.

    • Be cautious when used

    Use very carefully for people with liver disease, heart failure, severe deficiency of blood oxygen, severe respiratory failure, reduced blood volume or shock, incomplete heart block or bradycardia, and atrial fibrillation. In newborn or depressed.

    The ability to drive and operate machinery

    unused.

    Pregnancy

    can be used.

    Breastfeeding period

    can be used.

    Drug interaction

    Adrenalin in combination with lidocaine reduces absorption and toxicity, thus extending the time of the effect of lidocaine. Anesthesia such as Mexiletin, Tocainid, or Lidocaine used throughout the body or injected for local anesthesia will cause risk of toxic (due to the combination effect on the heart); And the risk of overdose (when using lidocaine or local anesthetic injection), if simultaneously applying and applying lidocaine on the mucosa in large quantities, used many times, used in the mouth and throat area, or swallowing.

    Beta, cimetidin blockers: simultaneously used with lidocaine can slow down lidocaine metabolism due to reduced blood flow in the liver, leading to an increased risk of lidocaine poisoning.

    lidocaine increases the effect of sucinylcholin.

    Storage

    The temperature does not exceed 30 ° C, avoiding light.

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