30% Glucose solution B.Braun temporarily reduces symptoms of increased intracranial pressure, hypoglycemic coma (500ml)
Dosage form 10 bottles x 500ml
Specifications Glucose monohydrate
Ingredient
Thành phần cho 500ml
| Composition information | Content |
| Glucose monohydrate | 165g |
Uses
indications
Glucose is indicated in the following cases:
glucose also helps maintain blood sugar levels and the synthesis of important components of the body. Insulin, glucagon, glucocorticoid and catecholamine are mainly related to the adjustment of blood sugar levels.
The normal state of electrolytes and acidic balance is a prerequisite for the best use of sugar. Therefore, in acidosis, it may impair oxidized sugar metabolism.
Metabolism of sugar and electrolytes is closely related. The demand for potassium, magnesium and phosphate may increase and therefore may need to be monitored and supplemented depending on the needs of the individual. If not provided, it can lead to impaired heart and neurological function.
Glucose intolerance can occur in cases such as diabetes and metabolic stress (for example, during and after surgery, serious illness, trauma). The severity of hyperglycemia and urinary glucose is related to the severity of pathological condition.
The transmission of high concentrations of glucose solutions can worsen brain damage and hiding in case of head injury, brain vessel injury and ischemic anemia.
pharmacokinetics
When the first transmission glucose will enter the circuit and then enter the intracellular.
During glucose hydrolysis is converted into pyruvat or lactat. Lactat can be partially put into glucose conversion (Cori ring).
In Pyruvate gas, fully oxidized into carbon dioxid and water. The final product of completely oxidation glucose is excreted in the lungs (carbon dioxid) and the kidney (water).
In fact, the sugar is not excreted through the kidneys in healthy people. In the status of pathological metabolism (such as diabetes) combined with hyperglycemia (blood sugar levels greater than 120 mg/100 ml or 6.7 mg/l), glucose is also excreted through the kidneys (with sugar in the urine) when exceeding the maximum ability to absorb through the tube (blood sugar levels greater than 180 mg/100 ml or 10mmol/l).
Before taking 30% Glucose solution B.Braun temporarily reduces symptoms of increased intracranial pressure, hypoglycemic coma (500ml)
How to use
Glucose 30% intravenously.
intravenously via intravenous catheter (for example, cavafix® intravenous line).
Dosage
Dosage and transmission speed of 30% Glucose are determined based on many factors including indications for use, age, weight and clinical condition of the patient.
30% glucose is used to intravenously after dilution or coordinated into a venous nutritional mixture. If not diluted, need to be transmitted through a central vein catheter.
Transmission of highly osmotic solutions can cause intravenous and intravenous irritation.
The osmotic pressure of the final solution after mixing must be noted when considering peripheral transmission.
Transmission speed and transmission volume depend on age, weight, clinical and metabolic condition as well as simultaneous treatment.
The transmission speed should be increased from the start of the product containing glucose.
To reduce the risk of hypoglycemia after stopping the transmission, it is advisable to slowly decrease the transmission rate before stopping the transmission.
Supplementing electrolytes can be indicated depending on the needs of the patient.
Based on indications for each patient, vitamins, trace elements and other ingredients (including amino acids and fats) can be added to intravenous infusion regimen to meet nutritional needs and prevent shortage and complications.
Dilute Glucose 30% before use, when transmitted with a source of amino acids (protein), will create a calorie ratio on the appropriate gram of nitrogen and have osmotic pressure suitable for the sugar. When 30% glucose intravenous fluid is used in combination with amino acids, glucose transmission speed must not exceed 1g/kg/hour to obtain optimal protein assimilation.
Used in pediatric patients
Transmission speed and transmission volume depend on age, weight, clinical and metabolic condition of patients, simultaneous treatment and should be decided by experienced doctors in the treatment of intravenous infusion in pediatric patients.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose?
Symptoms
Overdose can cause hyperglycemia, urine sugar, coma due to hyperglycemia or water penetration pressure in water and electrolyte disorders.
Emergency treatment, detoxification
The above -mentioned disorders may be treated by reducing glucose, using insulin and electrolyte auxiliary auxiliary.
What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.
Side Effects
When using glucose, you may experience unwanted effects (ADR).
The undesirable effects below have been reported in the circulating report, listed by Meddra System Organ Class (SC).
Systemic agencies group
Unwanted effects
Frequency
immune system disorders
Anaphylactic reaction
Unknown
Unknown
Hyperglycemia
Unknown
Rashes
Unknown
chills
Unknown
Unknown
Unknown Unknown
Unknown
thrombosis at the transmission position (accompanied by osmotic solutions). Unwanted effects are reported when glucose is used with intravenous nutrition: liver failure, cirrhosis, cholecyst, fatty liver, hyperlirubin blood, hyper enzyme, cholecystitis, precipitation gallstones in the right blood vessels. Instructions on how to handle ADR Notify the doctor with unwanted effects when using the drug.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Glucose 30% contraindicated in the following cases:
Precautions when using
Warning
The solution is not transmitted to the peripheral vein.
Venous infusion extends this solution that can cause inflammation of thrombosis spread from the transmission position.
dilute and other effects on serum electrolytes
Depends on the volume and speed of the transmission and depends on the basic clinical condition of the patient and the ability to metabolize glucose, glucose intravenous infusion may cause:
electrolyte disorders such as hypoglyc sodium, hypokalemia, hypoglycemia, hypoglycemia, blood stasis/increased blood volume (such as congestion, including pulmonary edema and pulmonary congestion).
The above effects are not only the result of the solution that does not contain electrolytes but also by glucose.
Hypoglyc sodium can lead to acute pungemia caused by hypoglycemia characterized by headache, nausea, epilepsy, sleep, coma, brain edema and death.
Children, the elderly, women, patients after surgery, patients with hypoxemia and patients with central neuropathy or thirst for many mental births have a special risk for this complication.
Clinical and subclinical assessments may be necessary to monitor changes in fluid balance, electrolyte concentration and acid-base balance during prolonged transmission treatment or whenever patient condition or transmission speed guarantees such assessments.
Special prudence especially for patients at risk of increasing water and electrolytes is more serious due to free water load, hyperglycemia or may be required to inject insulin (see below).
Hyperglycemia
For intravenous infusion of nutrients (for example, glucose, amino acids and fat) in general, the possible metabolic complications occur if the amount of nutrients inserted in does not suit the needs of the patient, or the metabolic ability of any nutritional component has not been appreciated correctly. Unwanted metabolic effects may occur due to incomplete transmission or too many nutrients or due to the composition of a mixture that is not suitable for the needs of the patient.
Quick transmission of glucose solutions can cause significant hyperglycemia and osmotic hypertension syndrome.
To reduce the risk of complications associated with hyperglycemia, adjust the transmission speed and/or insulin injection.
Be careful when glucose intravenous infusion in patients:
Thiamin shortage, for example, in chronic alcoholic patients (the risk of severe lactic acidosis due to pyruvate oxidation decline). Water and electrolyte disorders may be more serious due to glucose and/or increased water loads. The effect on insulin excretion prolonged glucose veins and hyperglycemia can lead to the consequence of reducing insulin excretion rate. Hypersensitivity reactions Hypersensitive reaction/transmission reaction, including anaphylactic reaction, has been reported (see unwanted effect section). The solution containing glucose should be used carefully in all patients with a history of allergies to corn or corn products. Infusion must be stopped immediately if there are any signs or symptoms that suspect is the hypersensitivity reaction. Appropriate treatment measures must be conducted according to clinical indications. Reproductive syndrome Restoration of severe malnutrition patients can lead to feeding syndrome, it is characterized by the change of potassium, phosphorus and intracellular magnesium due to the patient become assimilated. Thiamin deficiency and water retention can also occur. Careful monitoring and slowly increasing the nutrition and overeating to prevent complications. Liver disorders Bile disorders include bile stasis, fatty liver, fibrosis and cirrhosis, which can lead to liver failure, as well as cholecystitis and gallstones that occur in some intravenous feed patients. The causes of these disorders are caused by many factors and may vary each patient. Patients with abnormal test parameters or other signs of liver disorders should be evaluated early by a specialist to identify the causes and factors that contribute to possible, treatment therapies and preventive measures. Catheter infections and bleeding infections Infections and infections may occur as a result of the use of intravenous cathets to transmit nutrients, due to poor maintenance of catheter or due to contaminated solutions. Immune inhibitors and other factors such as hyperglycemia, malnutrition and/or basic diseases in patients can cause them to suffer from infection complications. Monitor symptoms and tests carefully for chills, leukemia, technical problems with access to access devices, and hyperglycemia can help detect early infection. precipitate precipitate in pulmonary blood vessels has been reported in patients raised to eat veins. In some cases, death has occurred. In addition, too much calcium and phosphate increases the risk of formation of phosphate calcium precipitate. The precipitate has been reported even without phosphate salt in the solution. In addition to checking the solution, the transmission line and the catheter should also periodically check the precipitate. If there are signs of respiratory failure, it is necessary to stop infusing and conduct medical evaluation immediately. Pediatric patients Transmission speed and transmission volume depend on the age, weight, clinical and metabolism of patients, simultaneous treatment, and should be decided by a consultant with experience in the treatment of intravenous fluid for pediatric patients. To avoid the possibility of death when infusion of infant intravenous fluid, special attention should be paid to the use. When using a pump to transmit liquid or intravenous medication to babies, liquid pity should not be connected to the syringe. When using the transmission pump, all the clamps on the intravenous line must be closed before removing the transmission lines from the pump, or fainting bombs. This is mandatory regardless of whether the line has a free fire -resistant device. Intravenous equipment and transmission equipment must be monitored regularly Issues related to blood sugar in pediatric patients Babies - especially premature babies and have low birth weight - have a high risk of lowering or hyperglycemia and therefore closely monitoring when treating with glucose solution to ensure adequate blood sugar control, to avoid unwanted long -term effects. Hypoglycemia in newborns can cause prolonged seizures, coma and lesions. Hyperglycemia is accompanied by cerebral hemorrhage, bacterial and fungal infections. retina in premature babies, necrotic bowelitis, bronchial products, prolonged hospital stay and death. Issues related to blood hypoglycetia in pediatric patients Children (including newborns and older children) are at risk of increased osmotic pressure decrease due to hypoglycemia as well as developing sodium hypoglycemia. The concentration of electrolytes in plasma should be closely monitored in pediatric patients. Quickly overcome the reduction of osmotic pressure due to hypoglycemia, which causes danger to the risk of severe neurological complications). Dosage, speed, and the time the media is determined by a doctor with experience in the treatment of intravenous fluids in pediatric patients. used in elderly patients When choosing the type of transmission solution and the volume of the transmission speed to the elderly patients, it is necessary to consider the elderly patients in general that they are more likely to suffer from heart failure, kidney failure, liver failure, and other diseases or use medications simultaneously. blood Glucose solution (a water solution, that is, the glucose solution does not have free electrolytes that should not be transmitted with the device used for blood transfusion, because hemolysis and fake red blood cell condensation may occur. unknown. Venous glucose transmission to the mother during labor can lead to insulin production in the fetus, related to the risk of hyperglycemia in the fetus and and metabolic acidosis as well as hypoglycemia in infants. Glucose solution may be used during pregnancy. However, be careful when the glucose solution is used during labor. Reproductive ability: There is no adequate data on the effects of glucose on fertility. There is no adequate data on the use of glucose solution when breastfeeding. Glucose solution is still being used during breastfeeding. Both effects on the blood sugar of glucose intravenously and its effects on water and electrolytes should be noted when using intravenous glucose in patients treated with other substances that work to control blood sugar, or fluid balance and/or electrolytes. The ability to drive and operate machinery
Pregnancy
Breastfeeding period
Drug interaction
Storage
Leave a cool place, avoid light, temperature below 30⁰C.
To be out of reach of children.
Each bottle is only used once. The non -use part must be canceled. Aseptic solution, no fever.
Do not use if the bottle is leaked or the solution is not transparent.
HSD: 36 months from the date of production.
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