7.2% Kidmin intravenous solution Otsuka provides amino acids due to renal failure (200ml)

Increasing weight smoothly, nitrogen balance regularly.

Normalization of blood amino and amino acid levels branched in muscle.

Increase input 15N - Leucin into the blood protein segment.

less nitrogen - urea in the blood.

The effect of Kidmin provides amino acids studied on mice cutting 7/8 kidneys with a non -protein diet and the following nutritional effects are recorded:

Improve nutritional status, proves by increased weight, nitrogen balance and normal blood amino.

There is no nitrogen - urea hyperkemen.

Dynamic pharmacokinetics

When transmitting Kidmin to mark 14 carbon for 12 -week -old healthy mice and mouse cutting 7/8 kidneys with total venous nutrition, seeing a quick distribution of the body throughout the body, 50 - 90% merged into the protein segments of plasma, muscles and main organs such as the liver, kidney and spleen from 3 to 72 hours after transmission.

The ratio of exhaled gases to exhale compared to the amount of marked substances transmitted in 32% in normal mice and 34% in the nephrotic cutting rats as up to 72 hours after transmission and the ratio of except for urine compared to the corresponding amount of quality transmitted substances is 4.6% and 4.9%.

The total dosage of nutrition on the gastrointestinal tract in adults is 600 ml of Kidmin solution per day, drip transmission through the central venous system.

Dosage is also adjusted depending on the weight, age and clinical condition of the patient.

Should provide over 300 kcal energy without protein on 1 g of nitrogen (100 ml of this product) so that the use of amino acids effectively.

Be careful:

(1) Due to the symptoms of hyper ammonia blood or consciousness disorders reported to occur when using amino acid injections for patients with renal impairment as a single source of amino acids, it is necessary to stop using this product immediately when there are abnormal signs including slow reaction when being called or greeted, or a temporary focus on driving or expressing ideas.

(2) Due to the symptoms of blood urea or metabolic acidic contamination may increase in case of inappropriate calories, patients should be closely monitored while taking the drug. If anything is abnormal, use appropriate measures such as stopping the drug.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Overdose

The metabolites of amino acids can be retained, so it can deteriorate the patient's clinical condition.

How to handle

If there is an overdose, the patient's condition should be re -evaluated and applied appropriate treatments.

What to do when forgetting 1 dose?

Not applicable.

Be cautious when using

be cautious when using Kidmin in the following cases:

Patients with cardiovascular disease.

Patients with liver dysfunction or gastric hemorrhage.

Patients with severe electrolyte balance disorders or acid - base balance.

Used in older adults:

Older patients often have impaired liver or cardiovascular functions, so it is necessary to closely monitor when used, reduce the dose by reducing the transmission speed.

Use in children:

Unknown safety when using kidmin in children (not enough clinical data).

In children, the physiological system for metabolism of amino acids can develop incomplete. Therefore should be cautious when using Kidmin for children such as reducing the speed of transmission.

Kidmin can cause hyperkalemia in mild infant. If there is an increased hemorrhage, the medication should be stopped, and the appropriate measures should be taken to reduce serum potassium.

Note:

Before opening a nylon bag, you need to check the color of the color indicator, do not use the bottle if the color indicator has turned blue or purple.

Using only one -time bottle, in case of non -transmission, remove excess solution.

Do not use bottles with fistula, cloudy or discolored holes

Do not use expired bottles recorded on the label.

The ability to drive and operate machinery

should be cautious because the drug can reduce focus temporarily when driving or expressing ideas.

Pregnancy

Unknown safety when taking this drug for pregnant women. Therefore, this medication should only be used for pregnant women and women who are likely to be pregnant if the benefits are more likely to occur.

Lactation period

Unknown safety when taking this medication for pregnant women. Therefore, this medication should only be used for pregnant women and women who are likely to be pregnant if the benefits are more likely to occur.

Interactive drug

Interaction with other drugs: No data has been recorded.

Cavalry: The physical and chemical properties of the drug solution may change (precipitate may appear) when combined with Kidmin with the following drugs:

Sustainable drugs in alkaline environment.

Water -soluble drugs.

If these signs appear not to use drug solutions.

To minimize the risk of a drug taboo when transmitting this drug with other drugs, check the turbidity and precipitate of the solution immediately after mixing the drug, before transmitting and checking periodically during the infusion process.