960ml Mg-TAN transmission provides water, electrolytes, amino acids and calories

Dosage form Bag x 960ml
Specifications Glucose, amino acids

Ingredient

Composition information	Content
Glucose	11%
Amino Acids	11.3%

Uses

Indications

960ml Mg-TAN infusion solution for indications for water, electrolytes, amino acids and calories to patients by intravenous injection for patients who cannot be nutritious by gastrointestinal tract or inappropriate digestive tract.

Pharmacokology

glucose

Pharmacological effects of infusion glucose are necessary as glucose provided by conventional foods.

amino acids and electrolytes

Pharmacological effects of amino acids and electrolytes are necessary like amino acids and electrolytes provided by conventional foods.

However, for amino acids through the path of eating, it will first go through the blood vessel and then go into the circulatory system, while the amino acids through the infusion path goes directly into the circulatory system

lipid

Lipid emulsion is a biological properties similar to endogenous fluids. Unlike conventional fluids, lipids do not contain cholesterol esters or apolipoproteins while phospholipid content is higher.

Metabolic lipid emulsion in the cycle is like normal endogenous fluids during metabolism.

The endogenous lipid particles are mainly hydrolyzed during the circulatory process and are posted by peripheral and liver LDL receptors. The ability to metabolize is determined by the components of lipid particles, nutritional status, disease and transmission speed.

In healthy volunteers, the ratio of emulsion lipid metabolism after transmission is 3,811.5g triglycerides per kg of body weight within 24 hours.

The ability to metabolize and oxidation rate depends on the clinical conditions of each patient, faster metabolism and increased absorption for patients after surgery and trauma, while patients with renal impairment and hyperglyceride blood, the ability to absorb endogenous lipids slower.

Dynamic pharmacokinetics

glucose

glucose provides and maintains normal nutritional state.

amino acids and electrolytes

amino acids are the components in the protein of pine foods, used to synthesize tissue proteins. If overdose will lead to elimination.

Research has shown the heating effect during amino acid transmission.

lipid emulsion

Lipid emulsion provides saturated and unsaturated fatty acids essential for energy metabolism and the structural integrity of the cell membrane.

emulsion at the appropriate dose does not cause changes in blood sugar. There is no clinical proof that refers to changes in lung function when lipids are used an appropriate dose.

The increase in liver enzymes in some patients during the infusion process but will disappear when the infusion stops. The above change process is similar to some other types of infusion without lipid emulsion.

Before taking 960ml Mg-TAN transmission provides water, electrolytes, amino acids and calories

How to use

mg-tan can be used for central or peripheral intravenous infusion.

Dosage

Dosage and transmission speed should be determined to suit each specific patient based on the ability to metabolize fat, glucose metabolism, weight, clinical condition and nutritional requirements of the patient. Should choose the type of packaging with a capacity suitable for the dose level for each patient.

Mg-tan dose is recommended for adults as follows:

Patients with normal diet, not high energy demand:

Drip intravenous injection at a dose of 0.7-1.0 g of total amino acid/kg weight/day (equivalent to 0.10–0.15 g of nitrogen/kg weight/day.

Patients with diets need a lot of energy: drip intravenous infusion at a dose of 1.0-2.0 g of total amino acid/kg of day weight (equivalent to 0.15-0.30 g of Nitrogen/kg weight/day.

Normally, the dose of 0.7-1.0 g of total amino acid/kg weighs daily or 0.10-0.15g of nitrogen/kg weight of the central or peripheral drip intravenous injection day corresponds to the dose of 27-40 ml of mg-tan/kg weight/day.

The injection speed must not exceed 3.7 ml/kg/hour (equivalent to 0.25g of glucose; 0.09g of amino acids and 0.13g of lipid/kg/hour), should be injected within 12 to 24 hours.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

How to deal with overdose drugs:

When these symptoms appear to stop immediately the transmission process for hemolysis or peritoneal jurisdiction.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Mg-tan may experience unwanted effects such as increased body temperature (about 3% of patients taking drugs) or symptoms such as headache, nausea, vomiting, dizziness (at less than 1% of patients taking drugs).

Also may experience other unwanted effects such as increased liver enzyme induction, thrombosis when infusion in peripheral vein.

Some unwanted effects are very rare when using the drug, including: symptoms of anaphylaxis (urticaria, rashes, chills, chills, hypotension, cyanosis, shortness of breath) or fat syndrome with symptoms such as hyperlemia, fever, liver pain, liver pain, lag

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Mg-TAN infusion solution 960ml contraindicated in the following cases:

Hypersensitivity to eggs, soybean protein or allergic to any ingredients of the drug. Blood is using insulin within 6 hours. acute myocardial infarction; metabolic acidosis; Severe blood infection, coma.

Be cautious when using

caution when using the drug in patients

Patients with lipid metabolic disorders; renal function; pancreatitis; liver function; Hypergian thyroidism has hyperglyceride blood, blood infections.

Patients with lactic acidosis; Supplying oxygen to cells is incomplete, dehydrated.

Patients with symptoms of electrolytes.

General notes when taking drugs

It is necessary to closely monitor clinically when starting to infect drugs to patients. When there is any abnormal signs, it is necessary to stop the infusion process immediately.

Before the infusion of the drug, electrolyte test should be poured to the patient to be able to specify the most appropriate dose.

To limit the risk of infection when injecting the tools must ensure aseptic, operations, procedures must be in accordance with the process.

Blood triglyceride concentration does not exceed 3 mmol/l within 5-6 hours after infusion.

Because the composition of the drug contains amino acids, it can increase micronutrients such as copper or zinc through the urinary tract, so it is necessary to consider adding micronutrients to patients who have to inject long -term drugs.

To limit the risk of taboos as well as the risk of blood clotting reactions, do not mix other drugs into infusion injection and should not be injected with other drugs while injecting Mg-tan.

While taking the drug, it is necessary to closely monitor the concentration of blood glucose, electrolyte, osmotic pressure of blood; Acid-base balance, electrolyte balance and liver function (alkaline phosphatase, ALT, AST) of the body.

When taking the drug for a long time, the body's blood formula and blood recipes are needed.

When infusion of drug infusion to patients with renal function, it is necessary to closely monitor the level of phosphate and potassium to be supplemented to the patient to prevent the risk of alkaline infection or metabolic acidosis.

Need regularly for patients to test the electrolyte to adjust the dose accordingly.

Note when using

Not used when the bag of the transmission bag has been broken.

Not used when sealing between parts of the transmission bag is torn.

Not used when glucose solution (solution A); Amino acid and electrolyte solution (solution B) is not transparent or fat emulsion (C) is homogeneous.

Mix the infusion fluids (A, B, C) before use.

Remove the remaining remaining medicine after infusion.

Using drugs in pregnant and lactating women

Using drugs in pregnant women: There is no data on the use of drugs in pregnant women should only take the drug if the benefits are superior to the risk.

Using drugs in breastfeeding women: There is no data for using drugs in nursing women should only take the drug if the benefits are superior to the risk.

Use drugs in infants: Do not use for babies.

The effect of drugs on driving ability, operating machinery

There is no evidence of the effect of the drug on the ability to drive, operate machinery.

Drug interaction

so far has not recorded clinical drug interactions, but there have been some reports on the following phenomena:

When used with insulin can affect the enzyme system.Clinically

, heparin dose may increase temporarily due to increased amount of lipoprotein lipase. The temporary increase of plasma lipolysis in the initial stage when taking the drug is due to the deceleration of triglyceride clearance.

Because soybean oil contains vitamin K1, it can affect the effects of anticoagulants of Coumarin, so patients need to be monitored to use these drugs while being treated with Mg-tan.

tests of bilirubin, lactate dehydrogenase, saturated oxygen, hemoglobin, ... in blood samples taken tested during the mg-tan infusion period can give inaccurate results due to being affected by lipid components. In most patients, blood samples taken after intravenous injection for 5-6 hours do not affect these tests.

Storage

Do not peel off the plastic bag. Store in closed boxes, at room temperature below 30 ° C. Do not freeze.

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