A Ame Bismo 15ml OPV oral discharge reduces unpleasant symptoms in the stomach, indigestion (20 packs)

Dosage form Box of 20 packs
Specifications Bismuth subsalicylat
Ingredient OPV Pharmaceutical Joint Stock Company

Ingredient

Thành phần cho 15ml

Composition information	Content
Bismuth subsalicylat	525mg

Uses

indications

Ambismo drugs are indicated in the following cases:

Reduces uncomfortable symptoms in the stomach, indigestion, heartburn and nausea. bicarbonate.

Bismuth Subsalicylate reduces the number of bowel movements, firmly stools, normalize liquid movement through anti -secretion, bacterial bonding mechanism of bacteria, and showing antibacterial activity in patients with diarrhea.

Dynamic pharmacokinetics

bismuth subsalicylate are transformed into bismuth carbonate and sodium salicylate in the small intestine.The oral biological use of Bismuth Subsalicylat is very low. Bismuth's distribution capacity in the tissue of the human body is very small. Although Bismuth is also excreted through bile, the renal clearing is the path of excretion of Bismuth. The rest of the drug is excreted in feces in the form of insoluble bismuth salt. After taking the maximum daily recommendations for adults, the average biological destruction time is about 33 hours and the peak concentration of bismuth in plasma is below 35ppb.

Salicylate absorbs through the intestine and quickly distributed into the body's tissues. The peak concentration in plasma after daily dose is about 110 micrograms/ml. Salicylat is rapidly excreted from the body and the average biological destruction time is about 4-5.5 hours.

Before taking A Ame Bismo 15ml OPV oral discharge reduces unpleasant symptoms in the stomach, indigestion (20 packs)

How to use

Chewing pills, do not use more than 2 days.

Dosage

Adults and children aged 12 and older: 2 capsules/time.

Can be repeated for more than 2 - 1 hour if needed, up to 8 doses in 24 hours. If the symptoms are still there, need to see a doctor.

Because diarrhea can cause dehydration, need to drink enough water to rehydration.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

How to handle: Causes vomiting or gastrointestinal, using activated carbon. Transfusion, dialysis, peritoneal or blood transfusion is necessary for serious overdose.

Monitor Salicylate concentration in serum until the drug concentration decreases below the poisoning level. Monitoring and treating the survival functions, monitoring the phenomenon of pulmonary edema and convulsions for appropriate treatment.

In case of emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using Ambismo may experience unwanted effects (ADR) such as:

Common, ADR> 1/100:

black stool or tongue dye, discoloring tooth discoloration (recovery).

Nausea, vomiting.

Rare, ADR

Kidney toxicity, brain disease, neurotoxicity.

Instructions on how to handle ADR:

Notify the physician with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

AMEBISBO drug contraindicated in the following cases:

Hypersensitivity to Bismuth Subsalicylat or any ingredients of the drug.

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Ambismo contains salicylat, if you take the drug with aspirin that appears tinnitus, should stop taking the drug. If diarrhea has a high fever or lasts more than 2 days, you should see a doctor. Kidney.

Severe liver disease can cause bismuth accumulation.

The effect of the drug on driving and operating machinery

No report.

Use drugs for women during pregnancy and lactation

Pregnant and lactating women: There is no adequate data on the use of drugs in pregnant women.

Animal studies are not enough for pregnancy, the development of embryos/fetuses, childbirth and postpartum development. Unknown risks for humans.

Do not use bismuth subsalicylat during pregnancy and breastfeeding unless really necessary.

Medicinal interaction

anticoagulant drugs: Salicylate salt (Bismuth Subsalicylate) may increase the risk of bleeding when used simultaneously with anticoagulant drugs. Need to monitor the anticoagulant treatment, adjust the anticoagulant dose when necessary.

Diabetes treatment: Hypoglycemic effects can be increased when used simultaneously with salicylate salt. Need to be careful when using combination.

Ciprofloxcain: Bismuth subsalicylate reduces the peak concentration in plasma and auc of ciprofloxacin.

doxycyclin: bismuth subsalicylate reduces the absorption of doxycyclin. Avoid using bismuth subsalicylat to self -treatment for travelers who are using doxycyclin to prevent malaria.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

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