Aceclofenac Stella 100mg pain reliever and anti -inflammatory in osteoarthritis (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Aceclofenac
Ingredient Acute renal failure, chronic kidney failure, peptic ulcer

Ingredient

Composition information	Content
Aceclofenac	100mg

Uses

Indications

Analgesic and anti -inflammatory treatment in osteoarthritis, rheumatoid arthritis and joints.

Pharmacokic

pharmacokinetics

absorption:

Aceclofenac is well absorbed through the digestive tract, the peak concentration in plasma is achieved from 1-3 hours after drinking.

Distribution:

Metabolism:

No information.

Era:

Selling waste time of plasma is approximately 4 hours. About 2/3 of the drug is excreted in the urine, mainly in the form of hydroxy metabolites. A small amount is converted to diclofenac.

Before taking Aceclofenac Stella 100mg pain reliever and anti -inflammatory in osteoarthritis (5 blisters x 10 tablets)

How to use

Dosage

Adults:

The recommended dose is 200 mg (2 capsules) per day, divided into 2 times, 100 mg each time, one tablet in the morning and one tablet in the evening.

Children:

There is no clinical data on the use of Aceclofenac in children so it is not recommended for children under 18 years old.

Elderly:

Because Aceclofenac's pharmacokinetics does not change in elderly patients, there is no need to change the dose or the dose frequency.

Patients with liver failure:

Need to reduce Aceclofenac dose for patients with liver failure and the initial dose is proposed to be 100 mg daily.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms:

Symptoms include headache, nausea, vomiting, injury area, digestive stimulation, gastrointestinal bleeding, rarely diarrhea, disorientation, agitation, coma, drowsiness, dizziness, tinnitus, lowering blood pressure, respiratory failure, fainting, sometimes seizures.

In case of severe poisoning, acute renal failure and liver damage.

Management:

Patients need symptom treatment. Use activated carbon within an hour after overdose in a large, so choose a gastric lavage within an hour after overdose is likely to be life -threatening.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Aceclofenac Stella 100 mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Nervous system: Dizziness

Digestive: indigestion, abdominal pain, nausea, diarrhea.

Metabolism: Increase liver enzymes

Uncommon, 1/1000

Digestive: flatulence, gastritis, constipation, vomiting, mouth ulcers.

Skin and subcutaneous tissue: itching, rash, dermatitis, urticaria.

Other: Hypertoinemia, increased blood creatinine.

Rare, 1/10000

Blood and lymphatic system: Anemia

The immune system: Anaphylactic reaction (including shock), hypersensitivity.

Eyes: visual disorders

Respiratory: Difficulty breathing

Digestive: black stool

Skin and subcutaneous tissue: Facial edema

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Aceclofenac Stella 100 mg is contraindicated in the following cases:

Patients with hypersensitivity to Aceclofenac or any component of the drug.

Patients with a history of progressive digestive ulcer or suspected digestive ulcers or gastrointestinal bleeding.

Patients with kidney failure moderate to severe.

Be cautious when using

gastrointestinal hemorrhage or digestive ulcer, vomiting blood and black stools often occur worse in the elderly. This condition may occur whenever treatment, with or without warning signs or a history of previous disease.

Must be tight medical supervision in patients with serious liver function failure.

Hypersensitivity reactions, including anaphylactic/ anaphylactic reaction, may occur without exposure to the previous drug.

Patients with mild kidney failure or heart failure and elderly patients need to be carefully monitored, as NSAIDs can cause impaired renal function, need the lowest doses to work and regularly monitor kidney function.

Use Aceclofenac for patients with patrophyrin metabolic disorders in the liver may activate the disease.

NSAID drugs are carefully used for patients with a history of heart failure or hypertension because edema has been reported related to the use of NSAIDs.

NSAID drugs can impair fertility and are not recommended for women who are planning to get pregnant, temporarily consider Aceclofenac for women who are difficult to conceive or are being intervened.

Use carefully for patients with or have a history of bronchial asthma because NSAID is known to cause bronchospasm in these patients.

The ability to drive and operate machinery

Unwanted effects such as dizziness, drowsiness, fatigue and visual disorders may occur after using NSAIDs. If using drugs, patients should not drive or operate machinery.

Pregnancy

Avoid using Aceclofenac during pregnancy unless the benefits are higher than the risk for the fetus.

The period of breastfeeding

According to the study so far, NSAID drugs can be present in breast milk at very low concentrations. If possible, do not use nsaids during breastfeeding.

Interactive drug

Other painkillers including cyclooxygenase-2 inhibitors: Avoid simultaneous use of two NSAIDs or more (including aspirin) because it can increase the risk of side effects.

Medicines for hypertension: Reducing the anti -hypertension effect of these drugs.

Diuretics, ciclosporin, tacrolimus: increases the risk of kidney toxicity.

cardiac glycosides: NSAID drugs can seriously cause heart failure, reduce glomerular filtration rate and increase plasma glycosides.

Lithi: Lithium elimination.

Methotrexate: Be careful when taking NSAID and METHOTREXAT drugs within 24 hours because NSAID drugs can increase the concentration of methotrexate in plasma leading to increased toxicity.

Mifepriston: Do not use NSAID drugs for about 8-12 days after using Mifepriston because NSAID drugs can reduce the effect of Mifepriston.

corticosteroids: Increased risk of ulcerative or gastrointestinal bleeding.

Anticoagulants: NSAID drugs can increase the effects of anticoagulants.

Quinolon antibiotics: NSAID drugs may increase the risk of convulsions due to quinolon antibiotics.

Platelet resistant agents and selective inhibitors recover serotonin (SSRIs): Increased risk of gastrointestinal bleeding.

Zidovudln: Increased risk of hematology.

Diabetes treatment: Consider to adjust the dose of drugs that reduce blood sugar.

Other NSAID drugs: simultaneously used with aspirin or other NSAID drugs may increase the frequency of side effects, including the risk of gastrointestinal bleeding.

Storage

In closed packaging, dry place, avoid light, temperature not exceeding 30 ° C.

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