Acemol 100mg Nadyphar medicine relieves pain, discomfort, fever (100 tablets)

Dosage form Box of 100 capsules
Specifications Acetaminophen
Ingredient Fever, body aches

Ingredient

Composition informationContent
Acetaminophen100mg

Uses

indicated

acemol is indicated in the following cases:

  • Treatment of fast pain relief with symptoms of fever, pain and discomfort such as headache, ear pain, toothache, pain caused by the flu. Aspirin; However, unlike aspirin, paracetamol is not effective for inflammation treatment.

    With the equal dose calculated by grams, paracetamol has analgesic and fever -reducing effect similar to aspirin.

    paracetamol reduces the body temperature in fever, but rarely reduces the body temperature in normal people. The drug affects the hypothalamus causing cooling, increasing heat due to vasodilation and increased peripheral blood flow.

    Paracetamol with treatment dose, less impact on the cardiovascular and respiratory system, does not change acid -base balance, does not cause irritation, scratches or stomach bleeding because paracetamol does not work on the body cyclooxygenase, only affects cycloxygenase and prostaglandin of the central nervous system. Paracetamol does not work on platelets or bleeding time.

    Pharmacokinetics

    absorption

    The type of oral oral is absorbed completely quickly.

    Distribution

    Linking drugs with plasma proteins reach a maximum concentration after 30-60 minutes. Paracetamol is quickly and evenly distributed in most body tissues. About 25% paracetamol in the blood combined with plasma proteins. Selling time in plasma from 1.25 hours to 3 hours.

    Metabolism

    paracetamol is metabolized in the liver under the effect of cytochrome P450 into metabolic and is quickly reduced by glutathion. Poisoning caused by this metabolite increases when high doses.

    Elimination

    paracetamol eliminated in the urine in the form of: combined with glucuronic acid (about 60%), sulfuric acid (about 35%), or cysteine ​​(about 3%) and a small amount of hydroxylation and reducing substances.

    • Before taking Acemol 100mg Nadyphar medicine relieves pain, discomfort, fever (100 tablets)

    How to use

    oral medication.

    Dosage

    Children 1-3 years old: 1 tablet each time, 4-6 times a day.

    Children 4 - 5 years old: 2 tablets each time, 4-6 times a day.

    Children 6 - 8 years old: 3 tablets each time, 4-6 times a day.

    Children 9 - 11 years old: Each time 4 tablets, 4-6 times a day.

    From 12 years of age: each drink 4-6 tablets, 4-6 times a day.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

    Symptoms

    Paracetamol poisoning may be due to a single -dose, or due to a large dose of paracetamol (7.5 - 10 g in 1-2 days) or for long -term medication. The liver necrosis depends on the dose is the most important toxic effect due to overdose and can be fatal. When using paracetamol overdose, a metabolic substance is N - acetylbenzoquinonimin, which is toxic to the liver.

    Excessive dose can cause decomposition of liver cells, metabolic acidosis, brain pathology leading to coma and death.

    Handling overdose

    Gastric lavage (preferably within 4 hours after drinking). The main detoxification is the use of sulfhydryl compounds, perhaps partly due to the supplement of glutathion reserves in the liver, N - acetylcystein, which works when taken or intravenously. Must give the drug immediately if less than 36 hours after taking paracetamol.

    Treatment with N - Acetylcystein is more effective when giving the drug for less than 10 hours after taking paracetamol. When drinking, dilute N - Acetylcystein solution with water or drinks without alcohol to achieve a 5% solution and must be taken within 1 hour after mixing. Give N - Acetylcysteine ​​at the first dose of 140 mg/kg, then give 17 more doses, each dose of 70 mg/kg 4 hours apart. Termination of treatment if the paracetamol test in plasma shows the risk of low liver toxicity.

    Can use methionin, activated carbon and/or salt bleach because they have the ability to reduce paracetamol absorption.

    What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

    Side Effects

    Acemol may experience the following side effects:

    Not determined frequency

  • Digestive: digestive disorders.
    • Hematology: Neutral leukopenia, anemia, rarely platelets.

    Other: allergies, skin rashes with roses or urticaria, toxic to kidneys.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    contraindicated

    Acemol is contraindicated in the following cases:

  • Hypersensitivity to paracetamol.
  • Lack of glucose - 6 - Phosphate dehydrogenase (G6PD).

    • Be cautious when using

    with children with severe renal failure, the time is separated between 2 times of taking the drug at least 8 hours.

    Do not use paracetamol to treat pain for more than 5 days or high fever, fever lasting more than 3 days in children unless the physician is instructed.

    Doctors need to warn the patient about signs of serious skin reactions such as Steven - Johnson syndrome (SJS), toxic skin necrosis syndrome (Ten) or Lyell syndrome, acute pustules syndrome (AGEP).

    The ability to drive and operate machinery

    The drug does not affect the ability to drive and operate machinery.

    Pregnancy

    Used for pregnant and lactating women.

    Breastfeeding period

    Used for pregnant and lactating women.

    Medicinal interaction

    Concentrated with anti -seizures (phenytoin, barbiturat, carbamazepin), isoniazid increases the toxicity of the liver.

    Long -doses of high -dose Paracetamol increases the anticoagulant effects of cooumarin and indoors. This effect is small or not clinically important, so paracetamol is used when it is necessary to relieve mild pain or reduce fever for patients who are using Coumarin and indandion.

    Storage

    At a temperature not exceeding 30 ° C, in a dry place.

    Other drugs

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    count views

    Popular Keywords