Acetylcystein 200mg khapharco mucus in bronchitis, viscous mucus (10 blisters x 10 tablets)

Dosage form Hard capsules
Specifications Box of 10 blisters x 10 tablets
Ingredient Acetylcysteine
Indication Cough with phlegm, acute bronchitis, chronic bronchitis
Contraindication Bronchial asthma

Ingredient

Composition information	Content
Acetylcysteine	200mg

Uses

Indications

Acetylcystein drugs are indicated to help eliminate mucus in viscous mucus, respiratory diseases with mucus mucus like acute and chronic bronchitis and regular cleansing in trachea.

Pharmacokology

Acetylcystein is the n-acetyl derivative of L-cystein, a natural amino acid.

The drug has the effect of eliminating the mucus due to the free sulhydryl, reducing the mucus of the phlegm in the pus or not by separating the disulfide bridge in mucoprotein and creating favorable conditions to expel the sputum by coughing, running posture or by mechanical methods.

pharmacokinetic

absorption

After taken, Acetylcystein is quickly absorbed in the digestive tract and reaches the peak concentration in plasma about 0.5 - 1 hour after oral the dose of 200 - 600 mg. Low oral bioavailability, about 4 - 10% dose.

distribution

83% of the drug is attached to plasma proteins.

transformation

Acetylcystein metabolizes in the intestinal wall and converts initially in the liver, has acetyl reducing liver into cysteine and is then converted.

Elimination

The sale time of the drug on average 2 hours. Kidney clearance can account for 30% of the whole body clearance.

Before taking Acetylcystein 200mg khapharco mucus in bronchitis, viscous mucus (10 blisters x 10 tablets)

How to use

oral tablets.

Dosage

Adults and children over 7 years old: 200 mg x 3 times/day.

There is no special requirement on drug treatment after use.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Hydropulation, respiratory failure, hemolysis, intravascular coagulation and kidney failure.

Management

Immediately transfer to the nearest medical facility for treatment, mainly symptomatic treatment.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Acetylcysteine has a large safety limit. Although rarely clinically bronchospasm in clinical due to acetylcysteine, it can still occur with all types of drugs containing acetylcysteine.

When using acetylcysteine 200 mg, you may experience unwanted effects (ADR).

Uncommon, 1/1000

The immune system: hypersensitivity. flow.

Systemic: Fever.

Digestive: indigestion.

The immune system: anaphylaxis, anaphylactic reaction.

Systemic body: Evaluation.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Acetylcysteine drugs are contraindicated in the following cases:

Hypersensitivity to acetylcystein or any ingredients of the drug.

Children under 2 years old.

Precautions when using

coughing is a basic factor to protect the bronchi, so it is necessary to be respected.

The combination of drugs that eliminate mucus with anti -cough drugs or dryness the secretion of mucus (the effect of atropine) is unreasonable.

To closely monitor patients with a risk of asthma if using acetylcysteine for people with a history of allergies. If bronchodial spasms must be used as bronchodilator spray such as salbutamol or ipratropium and must stop acetylcysteine immediately.

When treated with acetylcystein, there may be a lot of diluted phlegm in the bronchi, need to be smoked to remove if the patient reduces cough.

Be cautious in patients with peptic ulcer or have a history of peptic ulcer, especially when combined with drugs that irritate the gastrointestinal mucosa. If there is intense vomiting when taking the drug, it is necessary to monitor stomach bleeding, or esophageal dilatation, stomach ulcers.

Serious skin reactions such as Steven - Johnson syndrome and Lyell syndrome have been reported very rarely when using Acetylcystein. In most reports, it is used by acetylcysteine simultaneously with at least one other drug capable of stimulating the mucosa. To prevent, if skin damage or mucosa appears, should stop treatment immediately and consult a doctor.

In In vitro studies show that acetylcysteine can cause platelet aggregation. Clinical significance is unknown. Precautions in patients at high risk of bleeding.

The drug can clog the respiratory tract in children under 2 years old, due to the physiological characteristics of the respiratory tract in this age group. The ability to cough out sputum is limited. Therefore, drugs should not be used in children under 2 years old.

The drug contains lactose, so patients with rare genetic disorders in galactose tolerance, Lactose Lapp deficiency or Glucose - Galactose absorption disorders should not use this drug.

The star flour in the drug contains very low concentrations of gluten and almost no problem if the patient has Celiac's disease. The drug contains star flour so it is not used for patients with wheat allergies (different from Celiac).

Use drugs for women during pregnancy and lactation

Pregnancy

Animal research shows that it is not likely to cause teratogenicity. However, there has been no research to prove that Acetylcystein is safe on pregnant women. Therefore, only acetylcysteine is used for pregnant women when necessary.

Breastfeeding period

There is no data on whether the drug is excreted in breast milk, but due to low toxicity, the potential risk for children is negligible. Therefore, can be used for breastfeeding women.

The effect of the drug on the ability to drive and operate machinery

The drug causes unwanted effects such as drowsiness, headache, tinnitus. Therefore, acetylcysteine should not be used while participating in these activities.

Medicinal interaction

acetylcysteine is a reducing agent (reducing), so it is not used with oxidative drugs.

Do not use it simultaneously with other cough drugs or any drugs that reduce bronchial secretion during acetylcysteine treatment.

Due to the lack of studies on the correlation of the drug, not mixing this drug with other drugs.

Medication interactions can affect the activity of the drug or cause side effects.

Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

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