Acetylcystein 200mg khapharco pepper in bronchitis, viscous mucus (190 tablets)

Dosage form Hard capsules
Specifications Bottle of 190 tablets
Ingredient Acetylcysteine, starch, lactose, Povidone K30, Magnesi Stearat
Indication Acute bronchitis, chronic bronchitis
Contraindication Drug allergy

Ingredient

Composition information	Content
Acetylcysteine	200mg
Starch
Lactose
Povidone k30
Magnesi Stearate

Uses

Indications

Acetylcystein 200 mg drug is indicated in the following case:

Mucus in viscous mucus, respiratory diseases with mucus as in acute and chronic bronchitis and regular cleaning in the trachea.

The drug has the effect of eliminating the mucus due to the free sulhydryl, reducing the mucus of the phlegm in the pus or not by separating the disulfide bridge in mucoprotein and creating favorable conditions to expel the sputum by coughing, running posture or by mechanical methods.

pharmacokinetic

absorption

After taken, Acetylcystein is quickly absorbed in the digestive tract and reaches the peak concentration in plasma about 0.5 - 1 hour after oral the dose of 200 - 600 mg. Low oral bioavailability, about 4 - 10% dose.

Distribution

83% of the drug is attached to plasma proteins.

Metabolism

Acetylcystein metabolizes in the intestinal wall and converts initially in the liver, has acetyl reducing liver into cysteine and is then converted.

Elimination

The sale time of the drug on average 2 hours. Kidney clearance can account for 30% of the whole body clearance.

Before taking Acetylcystein 200mg khapharco pepper in bronchitis, viscous mucus (190 tablets)

How to use

Acetylcysteine 200 mg drug is taken orally.

Dosage

Adults and children over 7 years old: 200 mg x 3 times/day.

There is no special requirement on drug treatment after use.

What to do when overdose?

Symptoms

Hydropulation, respiratory failure, hemolysis, intravascular coagulation and kidney failure.

Handling

Immediately transfer to the nearest medical facility for treatment, mainly symptomatic treatment.

What to do when forgetting 1 dose?

Side Effects

Acetylcysteine has a large safety limit. Although rarely clinically bronchospasm in clinical due to acetylcysteine, it can still occur with all types of drugs containing acetylcysteine.

When using acetylcysteine 200 mg, you may experience unwanted effects (ADR).

Uncommon, 1/1000

The immune system: hypersensitivity. flow.

Systemic: Fever.

Digestive: indigestion.

The immune system: anaphylaxis, anaphylactic reaction.

Systemic: Evaluation.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Acetylcysteine 200 mg is contraindicated in the following cases:

Hypersensitivity to acetylcystein or any ingredients of the drug.

Children under 2 years old.

Precautions when using

coughing is a basic factor to protect the bronchi, so it is necessary to be respected.

The combination of drugs that eliminate mucus with anti -cough drugs and/ or dry the secretion of mucus (the effect of atropine) is unreasonable.

To closely monitor patients with a risk of asthma if using acetylcysteine for people with a history of allergies. If bronchodial spasms must be used as bronchodilator spray such as salbutamol or ipratropium and must stop acetylcysteine immediately.

When treated with acetylcystein, there may be a lot of diluted phlegm in the bronchi, need to be smoked to remove if the patient reduces cough.

Be cautious in patients with stomach -duodenal ulcers or a history of stomach -duodenal ulcer, especially when combined with drugs that irritate the digestive mucosa. If there is intense vomiting when taking the drug, it is necessary to monitor stomach bleeding, or esophageal dilatation, stomach ulcers.

Serious skin reactions such as Steven - Johnson syndrome and Lyell syndrome have been reported very rarely when using Acetylcystein. In most reports, it is used by acetylcysteine simultaneously with at least one other drug capable of stimulating the mucosa. To prevent, if skin damage or mucosa appears, should stop treatment immediately and consult a doctor.

In In vitro studies show that acetylcysteine can cause platelet aggregation. Clinical significance is unknown. Precautions in patients at high risk of bleeding.

The drug can clog the respiratory tract in children under 2 years old, due to the physiological characteristics of the respiratory tract in this age group. The ability to cough out sputum is limited. Therefore, drugs should not be used in children under 2 years old.

The drug contains lactose, so patients with rare genetic disorders in galactose tolerance, Lactose Lapp deficiency or Glucose - Galactose absorption disorders should not use this drug.

The star flour in the drug contains very low concentrations of gluten and almost no problem if the patient has Celiac's disease. The drug contains star flour so it is not used for patients with wheat allergies (different from Celiac).

The ability to drive and operate machinery

The drug causes unwanted effects such as drowsiness, headache, tinnitus. Therefore, acetylcysteine should not be used while participating in these activities.

Pregnancy

Animal research shows that it is not possible to cause teratogenicity. However, there has been no research to prove that Acetylcystein is safe on pregnant women. Therefore, only acetylcysteine is used for pregnant women when necessary.

Breastfeeding period

There is no data on whether the drug is excreted in breast milk or not, but due to low toxicity, the potential risk for children is negligible. Therefore, can be used for breastfeeding women.

Medicinal interaction

acetylcystein is a reducing (reducing), so it is not used with oxygen -chemical drugs.

Do not use it simultaneously with other cough drugs or any drugs that reduce bronchial secretion during acetylcysteine treatment.

Due to the lack of studies on the correlation of the drug, not mixing this drug with other drugs.

Storage

less than 30 ° C. Dry place, avoid light.

To be out of reach of children.

Other drugs

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