Aciclovir 800mg Meyer treat herpes zoster infection, chickenpox (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Acyclovir
Ingredient Herpes Simplex infection, herpes zoster, genital herpes

Ingredient

Composition information	Content
Acyclovir	800mg

Uses

indications

Aciclovir Meyer is indicated in the following cases:

The treatment of acute herpes infection (shingles), eye shingles, pneumonia caused by adult herpes zoster. Infection with herpes virus. The first, acyclovir is converted into Acyclovir monophosphate thanks to the enzyme of the virus, thymidinkinase. Then transform into Acyclovir Diphosphate and Triphosphate by some other cell enzymes. Acyclovir Triphosphate inhibits the synthesis of the virus DNA and the multiplication of the virus without affecting the metabolism of normal cells.

Acyclovir has the strongest effect on the Herpes Simplex Type 1 virus (HSV-1), inferior to the Herpes Simplex Type 2 virus (HSV-2), Varicella Zoster virus (VZV), the weakest effect on Cytomegovirus (CMV).

Dynamic pharmacokinetics

Absorption: Biological use of Acyclovir is about 20%. Food does not affect the absorption of the drug.

Distribution: Acyclovir is widely distributed in body fluids and organs. The maximum concentration of serum is achieved after 1.5 - 2 hours.

Metabolism: A small amount of drugs are metabolized in the liver, mostly discharged through the kidneys in the form of unchanged.

Elimination: Through the kidneys.

Before taking Aciclovir 800mg Meyer treat herpes zoster infection, chickenpox (3 blisters x 10 tablets)

How to use

Take oral use.

Dosage

Treatment of chickenpox and shingles

Adults: Take 1 tablet of 1 tablet/day, in 7 days.

Children over 6 years of age: Take 1 tablet 1 tablet/day.

Children under 6 years old: Should use Acyclovir 200 mg or Acyclovir 400 mg.

Specific dose as follows:

Children: Varicella disease: Take 20 mg/kg body weight/day (maximum 800 mg)

Children under 2 years of age take 200 mg x 4 times/day.

Children 2 - 5 years old: Take 400 mg x 4 times/day.

For patients with kidney failure, the elderly: The dose should be adjusted:

Creatinine clearance 10 - 25 ml/min: 1 hour after drinking.

Creatinine clearance below 10 ml/min: 1 hour by drink 1 time.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Treatment: Hemolyte from patients until kidney function recovers, stops drugs, gives water and electrolytes.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using aciclovir meyer, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: Nausea, vomiting, diarrhea, abdominal pain.

Mental: headache.

Skin and subcutaneous tissue: Ban skin.

Uncommon, 1/1000

Mental: Dizziness, confusion, hallucinations, drowsiness. This symptom is common in patients with renal impairment or there are factors that create a tendency.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Aciclovir Meyer drug is contraindicated in cases of people sensitive to drugs.

Caution when used

For patients with renal failure: The dose must be adjusted according to the creatinine clearance.

The ability to drive and operate machinery

can use drugs when driving and operating machinery. However, it is necessary to be cautious with patients with kidney failure because the drug can cause dizziness, hallucinations, confusion, drowsiness.

Pregnancy

should only be used for pregnant women when the benefits of treatment are more than risks that may occur for the fetus.

Lactation period

The drug is excreted by breast milk when used orally. Should be cautious when taking the drug for breastfeeding.

Drug interaction

Simultaneous use Zidovudin and Acyclovir can cause a state of sleep and drowsiness.

Probenecid inhibits competition to eliminate acyclovir through the renal tubules, so it increases by 40% and reduces excretion through urine and clearance of acyclovir.

amphotericin B and ketoconazole increase the anti -virus effect of acyclovir.

Storage

In a dry place, the temperature does not exceed 300C, avoiding light.

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