Acular Allergan eye drops temporarily itchy eyes due to seasonal conjunctivitis (5ml)

Dosage form Bottle
Specifications Ketorolac tromethamine
Ingredient Mold inflammation, itchy eye

Ingredient

Composition information	Content
Ketorolac tromethamine	0.5% W/V

Uses

indications

Acilar drugs are indicated in the following cases:

Temporarily reduce itchy eyes due to seasonal conjunctivitis.

Treatment of postoperative inflammation in the patient has been surgery to get opaque lens. The mechanism of action is partly due to the ability to inhibit prostaglandin biosynthesis. The small ketorolac tromethamine into the eyes will reduce the prostaglandin E2 (PGE2) content in the aquarium. The average concentration of PGE2 is 80 picogam/ml of the eye in the eye only small solution (does not contain active ingredients) and 28 picogam/ml of aquatic fluid in the eye has a small 0.5%acula solution.

Ketorolac Tromethamine uses the whole body without a pupil.

Acuit does not have a clear effect on glaucoma.

Acilar small eye solution is more effective than the conductive solution in reducing the itchy eye caused by allergic conjunctivitis.

Use a small acula eye treatment for patients for 2 weeks in a row, there are few signs of inflammation compared to the group of conductive certificates.

Dynamic pharmacokinetics

2 drops (0.1 ml) of 0.5% small acula eye solution into the eyes of patients 12 hours and 1 hour before surgery to get cloudy lens has achieved significant concentrations in the eye of 8 of 9 patients (the average ketorolac concentration is 95 ng/ml in aquaculture, at 40 to 170 ng/mL).

1 drop (0.05 ml) of 0.5% acula small eye solution into one eye and a drop of solution leading to the other eye 3 times/day in 26 normal people. Only 5 out of 26 people have the amount of ketorolac found in plasma (from 10.7 to 22.5 ng/ml) on the 10th day during local treatment. When using ketorolac tromethamine 10 mg of systemic sugar is 6 hours apart, the peak concentration in plasma is about 960 ng/ml.

Before taking Acular Allergan eye drops temporarily itchy eyes due to seasonal conjunctivitis (5ml)

How to use

ACULAR SMALL Use.

Dosage

The recommended dose of acula small eye solution is 1 drop each time (0.25 mg), 4 times a day to treat itchy eye caused by allergic conjunctivitis.

To treat postoperative inflammation in patients with surgery to get opaque lens, each drop of a small drop of acula eye solution to the eye needed to be treated, 4 times a day starts 24 hours after cataract surgery and continues the drug during the first 2 weeks after surgery.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? Not sure overdose occurs as recommended.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using acula you may experience unwanted effects (ADR).

In patients with allergic conjunctivitis, the most common side effect when using acular eye solutions is a fleeting burning feeling when the drug is small, this phenomenon is about 40% of patients. In all studies conducted, other side effects include eye irritation (3%), allergic reactions (3%), shallow infections in the eye (0.5%) and agricultural keratitis (1%).

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Acilar drugs contraindicated in the following cases:

Patients who already know is sensitive to any ingredients of the drug.

Be cautious when used

Has a cross -sensitivity with acetylsalicylic acid, derivatives of phenylacetic acid and other nonsteroidal anti -inflammatory agents. Therefore, be careful when treating patients who have manifested symptoms of these drugs. With some nonsteroidal anti -inflammatory pharmaceuticals, it has been found to increase bleeding time due to hindering platelet accumulation. The phenomenon of using nonsteroidal anti -inflammatory pharmaceuticals in the medical eye can cause increased bleeding in the eye tissue during eye surgery (including room bleeding).

Be cautious when using a small accle eye solution for patients is known to be tend to bleed or patients who are using other drugs that can extend the bleeding time.

Acilar small eye solution should not be used for patients carrying soft contact lens.

Cancer ability, gene mutations or fertility reduction: In an 18 -month study on mice with ketorolac tromethamine oral dose, equivalent to the maximum injection dose advised in humans (MRHD) and a 24 -month study in mice with 2.5 times the maximum dose of injection is advised in humans, showing that there is no sign of tumor creation.

Ketorolac tromethamine does not cause gene mutations in AMES testing, unneced DNA testing and recovery testing and mutant testing. In the small test of the In Vivo mouse, Ketorolac does not cause chromosomes. At 1590 µg/ml (about 1,000 average plasma levels in humans) and at higher concentrations, Ketorolac Tromethamine increases the influence of chromosomal deviations in Chinese hamster ovary cells.

Dosage of 9 mg/kg in male rats (53.1 mg/m2) or 16 mg/kg (94.4 mg/m2) in female mice does not hurt fertility.

has not determined the safety and effectiveness of this drug in children.

The ability to drive and operate machinery

When the eye is small, the eye may have fuzzy vision. Do not drive or use dangerous machinery until you see it clearly.

Pregnancy

There is no appropriate research and strictly tested on pregnant people. Therefore, Ketorolac Tromethamine is only used for pregnant women if the benefits for the mother will exceed the risk of the fetus.

breastfeeding period

Need to monitor carefully when using acula for nursing women.

Interactive drug

has a cross -sensitivity with acetylsalicylic acid, derivatives of phenylacetic acid and other nonsteroidal anti -inflammatory drugs. Therefore, be careful when treating patients who have manifested sensitive to this drug.

Acuit eye small solution is safe when coordinated with other drugs used in the scientific eye such as antibiotics, beta maple medications, carbon dioxide inhibitors, lash paralysis and pupils.

Storage

Store at temperatures below 30 ° C, avoiding light.

Other drugs

Disclaimer

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