Acuvail Allergan eye drops treat pain and inflammation after cataract surgery (30 tubes x 0.4ml)

Dosage form Box of 30 tubes x 12ml
Specifications Ketorolaco, ketorolac tromethamine
Ingredient Passable eye pain, pinkeye

Ingredient

Composition information	Content
Ketorolaco	5mg
Ketorolac tromethamine	4.5mg

Uses

Indications

Acuvail eye solution is indicated to treat pain and inflammation after cataract surgery.

Pharmacokology

Ketorolac Tromethamine is a nonsteroidal anti -inflammatory drug, when used the whole body, has been proven to effectively reduce pain, anti -inflammatory and anti -heat.

Its mechanism is thought to be due to the ability to inhibit prostaglandin biosynthesis.

pharmacokinetics

Two drops of small 0.5% small ketorolac tromethamine eye solution into the patient's eyes for 12 hours and 1 hour before cataract surgery to achieve an average Ketorolac concentration of 95 ng/ml in hydroponic 8 out of 9 eyes tested (about 40 to 170 ng/ml).

Put a drop of minor eye solution Ketorolac Tromethamine 0.5% into 1 eye and 1 drop into the other eye three times daily in 26 healthy objects. Five (5) out of 26 subjects with concentrations can detect ketorolac in their plasma (about 11 to 23 ng/ml) on the 10th day while on -site eye treatment.

The concentration after use three times daily of Ketorolac tromethamine small eye solution is approximately 4 to 8% of the minimum stability of the concentration in the last four daily drinking 10 mg ketorolac (290 ± 70 ng/mL).

Before taking Acuvail Allergan eye drops treat pain and inflammation after cataract surgery (30 tubes x 0.4ml)

How to use

ACUVAIL solution using small eyes.

Dosage

Dosage for patients

A drop of acuvail into the eyes 2 times daily, start a day before cataract surgery, continue to use on surgery day, and use during the first 2 weeks after surgery.

Dosage on surgery day by medical staff

about two hours before surgery, dripping about 20 minutes by medical staff with a total of three drops. Put one more drop before being discharged.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

The most common adultery reactions are reported in 1 - 6% of patients and include glaucoma, conjunctival congestion and/or hemorrhage, corneal edema, eye pain, headache, watery and vision.

Some of these reactions may be the result of cataract surgery.

The following side effects have been determined during the use of ketorolac tromethamine after being marketed include: bronchospasm, drama asthma attack, cornea perforation, thin cornea and corneal melting, disrupting epithelium.

Warnings

Contraindicated

Acuvail is contraindicated in patients with hypersensitivity to any component of the drug.

Precautions when using

Cross sensitivity

There is a possibility of cross -sensitivity with acetylsalicylic acid, derivatives of phenylacetic acid, and other NSAID drugs. Therefore, it is necessary to be cautious when treating patients who had previously been sensitive to these drugs.

bleeding

With NSAID drugs, bleeding time may be prolonged due to the impact on platelet aggregation. There has been a report that nonsteroidal anti -inflammatory eye can increase eye tissue bleeding (including room bleeding) during eye surgery.

Be careful when using acuvail eye solution in patients who know how to bleed or are taking other drugs that can prolong bleeding time.

Slow down the wound

Non -used non -steroid anti -inflammatory drugs (NSAID) can slow down or delay the healing process. Located corticosteroids have also been known to slow down or delay the healing process. Concomitant use of local NSAID drugs and locally used steroids can increase the ability to heal long wounds.

affect the cornea

Using local nsaids can cause keratitis. In some sensitive patients, continuous use of local NSAID drugs that can damage the epithelium, the cornea is thinner, corrosion, ulcers, or perforation. These effects can threaten vision. Patients with manifestations of cornea epithelium should stop taking NSAID drugs immediately and need to be closely monitored.

NSAID drugs used on the spot should be used carefully in patients with complex eye surgery, removal of corneal nerve, corneal epithelium defects, diabetes, eye surfaces (for example, dry eye syndrome), rheumatoid arthritis, or eye surgery several times in a short time may have increased risk of side effects on cornea and may threaten vision.

After -sales experience with local NSAID drugs also shows that the medication is more than 24 hours before surgery or more than 14 days after surgery can increase the risk of occurring and the severity of the cornea side effects.

Carrying contact lenses

Do not use acuvail while carrying contact lenses.

Eye damage and contamination

The patient should be directed to avoid the drop of the vial to touch the eyes or the structures around the eyes to avoid eye damage and eye drops.

Each bottle is only treated once for the eyes. Remove any remaining solution in the jar immediately after use.

used in children

Safety and efficiency in children under 3 years of age have not been determined.

Used in the elderly

Not observing the overall difference in safety or effectiveness between elderly patients and young patients.

The ability to drive and operate machinery

is not sure that it is influenced when using this eye drops, but it is necessary to warn the patient about the ability to be blurred while using acuvail, this phenomenon can affect the ability to drive and operate machinery.

Pregnancy

There is no adequate and controlled research in pregnant women. Acuvail should be used during pregnancy if the benefit is greater than the risk that may occur for the fetus.

Due to the known effect of prostaglandin inhibitors for the cardiovascular system (arteriosclerotic) fetus, it is advisable to avoid using acuvail in the late pregnancy.

Breastfeeding period

Because many drugs are excreted through breast milk, should be cautious when taking acuvail for nursing women.

Medicinal interaction

Acuvail eye small solution can be used simultaneously with other eye drops used on the spot such as alpha, antibiotics, beta blockers, anhydrase carbonic inhibitors, lashic paralysis and pupils. At least 5 minutes away from these acuvails.

Storage

at 15 - 300C. Store vials in the bag, avoiding light. Fold the packet closed after each use.

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