Acyclovir Stella Cream (5G) treatment for herpes simplex virus

Dosage form Cream
Specifications Tube
Ingredient Acyclovir
Indication Herpes Simplex is infected

Ingredient

Composition information	Content
Acyclovir	250mg

Uses

Indications

Acyclovir Stella Cream is used to treat the herpes simplex virus infection in the skin including lip herpes, the genital herpes onset and relapse.

Pharmacokological

Acyclovir is a similar substance Nucleosid purin with inhibited activity in vitro and Vivo virus Herpes Simplex Type 1 (HSV-1), Typ 2 (HSV-2) and Varicella-Zoster virus (VZV).

The inhibitory activity of acyclovir is highly selected by its affinity for thymidine kinase (TK) enzymes encoded by HSV and VZV. This enzyme converts acyclovir into acyclovir monophosphate, a substance similar to nucleotid. Monophosphate is transformed into diphosphate by the guiselate kinase of the cell and into triphosphate by some cell enzymes. In vitro, Acyclovir Triphosphate stops the DNA copy of herpes virus. This process occurs in 3 ways:

Inhibit competition with virus polymerase DNA.

cohesion and end the DNA chain of the virus.

Viral polymerase DNA.

Acyclovir's HSV activity is better than VZV's resistance due to its phosphorylation more effectively by the virus's enzyme.

pharmacokinetics

The whole body absorption of acyclovir is very low in skin so the blood concentration in the blood is below the detection limit. Therefore, the pharmacokinetic parameters of acyclovir cannot be used. Acyclovir is used not toxic to the skin because the drug does not access the circulatory system.

Before taking Acyclovir Stella Cream (5G) treatment for herpes simplex virus

How to use

Acyclovir Stella Cream is only used for skin.

Dosage

Follow the underwriting instructions unless there is a doctor prescribing Acyclovir Stella Cream. Follow these instructions and/or your doctor's instructions to be effective and safe in therapy with Acyclovir Stella Cream.

Apply a thin layer of cream to the damaged skin and adjacent 5 times/day, every 4 hours apart. near.

For the best response, Acyclovir Stella Cream should start as soon as possible, as soon as the first sign of Herpes (blistering, itching, discomfort, redness).

Treatment time: The doctor will decide how to continue using Acyclovir Stella® Cream 5G. Normally, continuous treatment for 5 days but depending on the individual and continue until the blisters are closed or healed. However, the treatment time does not exceed 10 days.

What to do when overdose? There is no report related to the overdose of the cream Acyclovir.

What to do when forgetting 1 dose? However, if the time of relaxation with the next dose is too short, skip the forgotten dose and continue the acyclovir Stella Cream. Do not use double dose to compensate for missed dose.

Side Effects

When using Acyclovir Stella Cream, you may experience unwanted effects (ADR). Applying Acyclovir Stella Cream may have a hot feeling, a glimpse of the needle in the treated skin. Occasionally red, dry, scaled in the treatment area.

Rarely skin reactions (contact dermatitis) after taking Acyclovir Stella Cream. The test of the skin's skin allergies has shown that most of the skin reactions are due to excipients rather than the active ingredient Acyclovir. It may be painful due to contact dermatitis if the above side effects occur clearly and on the skin wider than the skin treated with medicine.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using Acyclovir Stella Cream you need to read the instructions carefully and refer to the information below.

Contraindicated

Do not use Acyclovir Stella Cream for people who are hypersensitivity to acyclovir, valacyclovir or any ingredients of the drug.

let the doctor know before the beginning of treatment if the immune system is seriously damaged (meaning the body's immune system is seriously weakened).

Be cautious when using

The treatment starts as soon as possible immediately after being infected, preferably during the first phase of symptoms or damage.

Patients should wash their hands before and after applying the drug, avoid rubbing on the wound when not needed or using a towel to avoid worse or infection.

Do not apply cream to the mucosa as inside the mouth, vagina or eye. Be careful to avoid exposure to the eye.

Not for patients with immunodeficiency such as infection, bone marrow transplant or cancer treatment, unless the doctor's advice.

Instruct patients to avoid close contact with people with signs or symptoms of Herpes Simplex infection. There is no evidence of the use of Acyclovir external use will prevent the infection of HSV to others.

Safety and effectiveness when using cream Acyclovir in children under 12 years old has not been verified.

The ability to drive and operate machinery

No report.

Pregnancy

There is no information on the effectiveness of the use of Acyclovir Stella® Cream 5G during pregnancy in humans.

Breastfeeding period

although it is not known whether Acyclovir Stella Cream is distributed into breast milk after local use, but when used orally or intravenously, this drug is distributed into breast milk. Therefore, careful use of Acyclovir Stella Cream in nursing women. The mother has lesions caused by herpes to start near or on the chest should avoid breastfeeding.

Drug interaction

No interaction with other drugs for Acyclovir Stella Cream is used outside.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children.

Other drugs

Disclaimer

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